Evaluation On The Prediction Effect Of Hypocalcemia Using PTH Levels Detection In Different Time After Total Thyroidectomy

Objective Hypoparathyroidism after thyroidectomy is oneof the most common complications lead to hypocalcemia inclinical practice,which often related to serious complicationsand longer hospital stays.Through discussions thethyroidectomy and parathyroid hormone (PTH) level of1hoursafter the total thyroidectomy,to clarify whether PTH canpredict the hypocalcemia in the early24hours.Thus to find outa simple and reliable indicators to predict thepostoperativehypocalcemia,through the indicator we can reduce the risk ofhypocalcemia,and give preventive drug treatment in patientswith early hypocalcemia, to avoid the occurrence of adverseconsequences.Methods Review138patients with thyroid carcinomaresections,through continuous determination the level of the serum calcium (Ca2+) and PTH in postoperative1hours,6hours,24hours.Measuring the specificity,sensitivity, thepredictive value of negative and positive of PTH after1hourspostoperatively,to predict the occurrence of hypocalcemia in24hours postoperatively.Results This study reviewed138cases of thyroidpatientsafter hysterectomy,including36case(26.1%) occurredhypocalcemia (Ca2+<2.05mmol/l) in24hours after the totalthyroidectomy.The patients whose PTH <15pg/ml in1hourspostoperatively occurred hypocalcemia in24hours,of which thesensitivity,specificity,positive and negative predictivevalues were88.9%,100%,96.2%and100%respectively.Condusion The study found that the levels of PTH can predictthe early postoperative hypocalcemia after total thyroidectomyin24hours.The early treatment for the patients,such ascalcitriol,can avoid the risk of severe hypocalcemia.Patientswith early PTH hypocalcemia with in the safe scope does notaffect its discharge,so we proposed early preventionmanagement of hypocalcemia.