Study On The Prevalence Rate And Related Influencing Factors Of Osteoporosis In Zhuang Nationality Nationality Elderly Population In Wenshan Area

Objective:1.The use of dual-energy X-ray absorptiometry measurements Wenshan Zhuang nationality bone mineral density in the elderly population, combined with its history, investigate the incidence of Wenshan Zhuang nationality elderly population with osteoporosis.2. The combination of Wenshan Zhuang nationality basic personal signs in the elderly population, living environment and daily habits, to explore the risk factors of Wenshan Zhuang nationality elderly population the incidence of osteoporosis, for the Wenshan Zhuang nationality osteoporosis in the elderly population osteoporosis prevention and diagnosis to provide a reference.3. Determination of Wenshan Zhuang nationality osteoporosis in the elderly population serum markers of bone metabolism, understand the variation and predict the occurrence of osteoporotic fractures.Methods:The use of modern epidemiology stratified random sampling method,extraction of village each one according to the economic condition(good, medium and poor).Age≥40 years were randomly selected 124 cases of Zhuang nationality people, with 10-year-old age group as a grouping of subjects,and do bone mineral density test、basic sign measurements、osteoporosis-related factors questionnaire, then choose which part of the subjects were 72 cases to detect serum VDR, BGP, NTX, CTX.The data were statistically analyzed.Results:1.Wenshan Zhuang overall prevalence of osteoporosis in the elderly was 8.1 percent,6.0 percent prevalence rate among males, female prevalence was 9.5% higher in women than men, but the difference was not statistically significant.Male and female overall prevalence of osteoporosis with age is rising, men、women of different age groups was not statistically significant prevalence, males and females in each age group prevalence of osteoporosis showed no statistical significance.2.Wenshan Zhuang men and women, bone mineral density T value with age overall downward trend, men 60 to 69 and 70 to 79 age group and other age group differences were statistically significant (P<0.05), women 40 to 49 years age group and other age group difference statistically significant (P<0.05). Women in all age groups BMD T-score lower than males,60 to 69 and 70 to 79 age group of women and men in bone mineral density T-score difference was statistically significant.3.Wenshan Zhuang nationality elderly population age and male、female bone mineral density T values are negatively correlated (r=-0.551, P<0.01; r=-0.607, P <0.01),Hypertension and male, female bone mineral density T values are negative correlation (r=-0.387, P<0.01; r=-0.234, P<0.05), educational leveland male、 female bone mineral density T values are positively correlated (r= 0.411, P<0.01; r= 0.327, P<0.01), waist circumference and male、female bone mineral density T values are positively correlated (r= 0.294, P<0.05; r= 0.253, P<0.05), hip circumference and male、female bone mineral density T values are positively correlated (r=0.383, P <0.01), eating soy products, alcohol and male bone mineral density T values are positively correlated (r= 0.438, P<0.01; r= 0.324, P<0.05), tea and male bone mineral density T values are negative correlation (r= 0.363, P<0.01), weight、body mass index、OSTA index and female bone mineral density T values are positively correlated (r= 0.656, P<0.01; r= 0.609, P<0.01; r= 0.611, P<0.01), vegetarian food、taking hormones、 pregnancy、parity and female bone mineral density T values are negatively correlated (r=-0.270, P<0.05; r=-0.378, P<0.01; r=-0.365, P<0.01; r=-0.393, P<0.01). The average OSTA index is -2.279±3.9704 with osteoporosis.4.Wenshan Zhuang nationality elderly VDR level overall upward trend with age, overall fluctuated between 35.05±20.74～48.74±22.69pg/ml. Men appear BGP highest level in 50～59 years of age, was 1.86±1.52ng/ml, the highest level of female BGP 40～49 years of age, was 1.34±1.08ng/ml, followed by a slow decline. NTX, CTX levels were increased gradually with age, NTX overall volatility in 0.43±0.26～0.67±0.23nmBCE/mlL, CTX overall volatility in 0.24±0.89 0.35±0.13ug/L. VDR, BGP, NTX, CTX and age, osteoporosis correlation was not statistically significant.Conclusion:1.Wenshan Zhuang prevalence of osteoporosis in the elderly in general are lower than similar coverage levels, female prevalence in men.2.Wenshan Zhuang elderly BMD T value overall decreased with age, the prevalence of osteoporosis overall upward trend with age. After the 60-year-old male was significantly decreased bone mineral density T and women was 50 years of age, the main reason is closely related to decreased estrogen in postmenopausal women.3. High age、hypertension、low education level are the common risk factor for osteoporosis in the elderly Wenshan Zhuang nationality,male osteoporosis risk factors as well as tea, women’s risk factors for osteoporosis as well as vegetarian、take hormones、number of pregnancies、productive times, appropriate waist, hip are the common protective factors for osteoporosis in the elderly Wenshan Zhuang nationality,and protective factors for female osteoporosis as well as eat soy products、 moderate consumption of alcohol,the protective factors for male osteoporosis as well as the appropriate weight、body mass index.4.Wenshan Zhuang nationality elderly population OSTA index below -2.3, should be highly alert to osteoporosis.5.Wenshan Zhuang elderly VDR level overall upward trend with age, men 60 years ago continue to strengthen bone formation, followed by a slow decline, women 50 years ago continue to strengthen bone formation, followed by a slow decline, after 40 years old, male Women continued to strengthen bone resorption, but overall in the low bone turnover.Bone metabolism markers which can reflect the basic situation BMD T value.6.Well Wenshan Zhuang nationality masses osteoporosis prevention should be strengthened grassroots advocacy work related knowledge, comprehensive interventions to osteoporosis-related risk and protective factors, controlling the controllable risk factors and strengthen protective factors, dynamic monitoring bone turnover markers, given the appropriate anti-osteoporosis therapy, reduce and delay local elderly Zhuang nationality masses osteoporosis and osteoporotic fractures.