| Objective: Statistics of CHB(ALT < 2 ULN) in patients with clinical symptoms and signs appear frequency, rule, system analysis of CHB(ALT <2ULN) group of syndromes distribution and TCM syndrome type and the relationship between various influencing factors, and the correlation between TCM syndrome type and physicochemical indexes, for clinical for CHB(ALT <2ULN) provided a reference for diagnosis and treatment.Methods: Using TCM clinical information collection system records of 150 cases of CHB(ALT < 2ULN) in patients with clinical symptoms, signs, and according to the current diagnostic criteria, combined with the Israeli measurement certificate, in order to effect of the method of TCM for patients with classification, application subject to provide the data mining technology based on statistical analysis of the clinical signs and symptoms, extraction, explore the inherent law.Results:1. The total statistics major clinical syndrome of 27, according to the frequency of size top 10 syndromes are: general fatigue, pain, loss of appetite, abdominal distension, dry mouth, dry eyes, thin, defecate pond urine yellow,not mei, modern depression. The most common for red tongue, tongue reddish tongue; The tongue coating is thin, yellow moss; the most common The most common for the string of arteries and veins, heavy vein pulse condition.2. The TCM syndrome type is divided into six kinds, according to the occurrence frequency size is: damp and hot accumulate knot type > > change the type liver depression and qi stagnation type > liver-kidney Yin deficiency type > blood stasis resistance winding type > spleen kidney Yang deficiency type.3. The six groups of TCM syndrome types, liver depression and qi stagnation type of patient’s age and course of the youngest, spleen and kidney Yang deficiency type patient’s age and course of the disease. Change the age, course of the disease compared with other groups was statistically significant(P < 0.05), the other is no statistical significance between groups.4. The incidence of chronic hepatitis b(ALT < 2 uln) sex ratio has significant difference(P < 0.05); Each card type there was no significant difference between gender composition is(P > 0.05).5. Six groups of TCM syndrome types, damp and hot accumulate knot type HBe Ag positive rate is highest, spleen and kidney Yang deficiency type positive rate lowest, damp and hot accumulate knot type and change the type to compare difference was statistically significant(P < 0.05), comparing differences between the rest of the card type had no statistical significance(P > 0.05);6. Six groups of TCM syndrome types, damp and hot accumulate knot type- HBV DNA positive rate is highest, spleen and kidney Yang deficiency type positive rate lowest, damp and hot accumulate knot type compared with blood stasis type winding resistance difference was statistically significant(P < 0.05); There was no statistically significant difference compare between other syndromes(P > 0.05).7. Six groups of TCM syndrome types in the liver depression and qi stagnation type B ultrasonic like figure best result, spleen and kidney Yang deficiency is the worst result, 75% of patients with ultrasound results for chronic liver disease(or enlargement of the liver parenchyma echo), consistent with the physical and chemical indicators. 25% of patients with ultrasound results No obvious abnormal.Conclusion:Based on 150 cases of chronic hepatitis b(ALT < 2 uln) investigation we can get the following preliminary conclusions: in patients with damp and hot accumulate knot for most often witness, and the highest of HBe Ag and HBV-DNA positive rate; Liver depression and qi stagnation type onset age, the shortest duration; The ultrasound results best; Incidence of chronic hepatitis b(ALT < 2 uln) have bigger difference, the male incidence of a disease is significantly higher than female, each card type gender composition with no difference between the overall incidence of a disease. |
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