Clinical Observation Of Residual Burn Wounds With Blue Light(460nm)

Objectives Through the comparison of wound contraction rate and the bacterial culture positive rate between the experimental group(460 nm blue light irradiation therapy) and control group(missed by light therapy), preliminary evaluate the application valua of 460 nm blue light in the treatment of residual burn wounds.Methods 30 cases with 60 residual burn wounds, whose total area of the residual burn wounds is less than the 10% TBSA, all the patients were treated in the Department of Burns and Plastic Surgery, Tangshan Workers’ Hospital from January 2014 to December2014. Standard of group:the wound has not healed after 8 weeks of burn(after surgery or none surgery),each patient choice 2 wound areas, the condition of the granulation,anatomic site are similar roughly, 2 wounds can be partitioned not less than 50 cm, and the single wound is not exceeding 20cm2. Exclusion criteria:No serious systemic infection, acute metabolic disorders, diabetes, no serious heart, lung, liver, kidney and hematopoietic system comorbidities, pregnant and lactating women, no poor compliance and could not finish the course of treatment of patients, no scar ulcer patients.Two groups were divided according to the principle of self control. The way to draw the group: according to the relative position of the wound place(up, down or left, right) to do signed, the one which is lotted was pumped into the experimental group. Two groups were treated by different treatment methods.the experimental group: After routine cleaning the wound dressing,460 nm blue light irradiation for 10 minutes with irradiation distance 10cm(radiation is 60 m W/cm2), each day lasting for 28 days; the control group: Cleaning the wound dressing by conventional therapy. Both groups of patients were taken photographs at the beginning and on the 7th day, 14 th day, 21 th day and 28 th day by digital photographic camera paralleled to the wound(ruler was placed beside the wound). Using Image J image analysis software to measure the wound area, calculate healed wound area, and calculate wound healing rate. The wound contraction rate =(the original area-residual area) / original area ×100%. Both two groups of patients were documented at the beginning and on the7 th day, 21 th day line wound secretion bacteriological culture, count the positive strains and compare bacterial clearance rate. The bacterial culture positive rate =(removal bacteria number / initial bacteria number)×100%.Comparative observation of the wound of the experimental group and control group.Using SPSS17.0 statistical software to analysis the wound healing rate and the bacterial clearance rate. Measurement data using mean ± standard deviation( ±s), Measurement data between the two groups were compared by paired t test. Small sample count data were analyzed by F test,P<0.05 was statistically significant.Results Compared with the experimental group and the control group in the treatment of residual burn wounds, there was significant difference between the wound contraction rate(P < 0.05), the experimental group showed better than the control group; there was statistically difference(P < 0.05) between the bacterial culture positive rate, the experimental group was lower than the control group.Conclusions Using 460 nm blue light photo-radiation treatment in the residual burn wounds at the later stage of burn can accelerate wound healing and reduce the bacterial colonization. The blue light is cheap and safe, and can be used as a safe and effective treatment for residual burn wounds.