Epidemiological Survey Of Prevalence Of Fatty Liver And Its Riskfactors In Physical Examination Group Of Yan’an

ObjectiveTo investigate the prevalence rate and main r risk factors of fatty liver among adult residents in Yan’an,and to learn about the overall the prevalence of fatty liver and its trend of change in check-up peoples of Yan’an university affliated hospital from 2011 to 2014. Methods6236 random physical examination data of from check-up peoples of Yan’an university affliated hospital from February 2011 to March 2013 and all physical examination data of from check-up peoples of Yan’an university affliated hospital from 2011 to 2014 were choosed. The collected date include general characteristics,general examinations, complete blood biochemistry,abdominal Doppler ultrasonic and electrocardiogram.The data were input into database with SPSS19.0 software, and carried out descriptive analysis. the prevalence,major risk factors and trend of change of fatty live among adult residentsin yan’an and was analyzed by t-test,χ2 test, logistic regression analysis to investigate. ResultsA total of 6236 residents took part in the survey,which accounted for 3.76/1000 of Yan’an municipal residents.These patients included 3532 males and 2704 females.The mean age of the check-up peoples was 49.27±12.93 years(16-88).Fatty liver was diagnosed by ultrasound examination in 1602 patients(25.68%),among which 4.55% was alcoholic fatty liver,7.08% was suspected alcoholic fatty liver,and 88.37% was nonalcoholic fatty liver.The obesity, hyperuricemia, hypertension,fasting serum glucose level, the presence of obesity,diabetes mellitus,and dyslipidemia in the fatty liver group was significantly higher than those in the group without fatty liver(all P<0.001).The prevalence of FLD was not significant diference in males and in females.The prevalence rate of fatty liver presented a growing trend with aging in females.Among these peoples younger than 50 years old, the prevalence rate of fatty liver in males was significantly higher than that in females,but in these peoples older than 50 years the case was just the opposite,higher in females. There was statistical difference in the prevalence of fatty liver with n diferent occupational group. Those from governmental offices occupies a higher prevalence rate than the others,and those from farmer occupies lowest prevalence rate.Multiple regressionanalysis showed that age, male sex,waist circumference,heavy drinking, triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),fasting glucose, UA, body mass index(BMI),fasting serum glucose level,diabetes mellitusand hypertensionwere risk factorsfor fatty liver disease, buthigh-density lipoproteincholesterol(HDL-C) is a protective factor forfatty liver. Compared with normal group, risk offatty liver disease was increased by 1.58 and 2.63 times in IFG(impaired fasting glycaemia) groupand diabetes group respectively(P < 0.001); therisks for fatty liver disease in overweight, obesityand severe obesity groups were increasedby 1.62, 1.79, 9.54 times, respectively(P < 0.001); therisks for fatty liver disease in moderate drinking and heavy drinking were increasedby 1.63,3.64 times, respectively(P < 0.001); therisks for fatty liver disease in obesityand heavy drinking were increasedby 17.67 times.The prevalence rates of FLD from 2011 to 2014 with the constant check-up peoples in physical examination center of Yan’an university affliated hospital and yanchang oilfield were 21.75%, 23.82%, 26.18%and 27.95% respectively,which presented a growing trend year after year. The prevalence of FLD in The prevalence of FLD was not significant diference in males and in females The prevalence of FLD in these people was not significant diference in males and in females from 2011-2003,while the prevalence of males was significantly higher than female in 2014( X2=3.949,P<0.05).The prevalence of FLD was significant diference in different occupational group and different years(P <0.01),. The prevalence rates of FLD in workers, governmental offices and those from culture and education and health was going up year after year,while the prevalence of farmer had no obvious change(P>0.05). The prevalence of disease associated with fatty liver that included obesity,hypertension,diabetes mellitus, dyslipidemia, abnormal liver function demonstrateed an increasing trend In singulos annos. ConclusionThere is a high prevalence of fatty liver among adultresidents in Yan’an, and nonalcoholic fatty liver is the major type. The gender,age,obesity,heavydrinking,the metabolic disorder of bloodglucose, hyperuricemia, hypertension,and Dyslipidemia crease the risk for fatty in Yan’an.With the elapse of time, the prevalence rate of fatty liver and the prevalence of chronic diseases associated with fatty liver showed a growing tendency year by year,which indicated that the work about health education and prevention and treatment of FLD inYan’an was still unsatisfactory,and we ought to take necessary measures that included drawing a reasonable and personalized intervening measure, actively developing health education, strengthening propaganda about fatty liver-related knowledge for Yan’an public thereby for ultimate improving high prevalence of fatty liver and a rising trend of prevalence of fatty liver year by year.