Analysis Of Clinical And Pathogenic Bacteria Of Children With Urinary Tract Infection

Objective To investigate the clinical features,the pathogen distribution, change and resistance to common pathogenic bacteria of hospitalized children with urinary tract infection(UTI), and to guide the clinical treatment and medication.Methods Collection of Ningxia Medical University General Hospital Department of Pediatrics from January 2008 to December 2013 admission of 223 children with UTI and clinical features, laboratory and imaging findings and disease outcome were retrospectively analyzed. Focus on the analysis of urine culture results.Results Sex distribution varies with age children with UTI, 3 years of age for boys, girls are often seen over 3 years old. Systemic symptoms more common in infants, children mainly with urinary irritaton symptoms. 39.49% in this group of patients with congenital or acquired structural abnormalities of the urinary tract, such as hydronephrosis, renal pelvis and ureter stenosis, kidney stones, etc, Statistical analysis showed that the presence of children of different ages incidence of complications was significantly different, more common in <3 years old children; occur on a significant difference in gender complications in children, more common in male children. The group of 223 patients with urine culture were detected in 178 strains of bacteria, mainly gram-negative(G-) bacteria(70. 22%), of which the most common is Escherichia coli(53.93%); Gram-positive(G-) accounted for 28. 65% of bacteria, Enterococci in feces most common(12.35%) and Enterococcus faecalis(4.49%). Compared to 2008-2010 and 2011-2013, G-bacteria and G-bacteria population distribution and the distribution of the top five pathogenic bacteria, found that the G-bacteria infection rate has been higher than G-bacteria; there is an increasing trend in G-bacteria compared with the previous three years, Enterococcus faecium was significantly increased(P<0. 05). In G-bacteria, Escherichia coli resistant rate to ampicillin, piperacillin/tazobactam, nitrofurantoin, cefotetan, ceftazidime is more sensitive to piperacillin, all sensitive to imipene; G-bacteria resistant Enterococci in feces is relatively complex, which choose a more sensitive to vancomycin, linezolid, teicoplanin.Conclusions The clinical symptoms of UTI in children varies according to age, performance of varying severity, should strengthen the awareness for this disease; diagnosed no consolidation should be taken to exclude urinary tract deformities, and prevent complications. Children with UTI pathogen still with Escherichia coli as the common pathogenic bacteria; G+bacteria have a rising trend, mainly enterococci in feces. Clinical should pay attention to the cultivation of the middle urine, strengthen the monitoring of pathogens and their drug resistance, in order to rationally choose sensitive antibiotics and reduce the occurrence of drug resistant bacteria.