The Influence Of Uterine Surgery On The Ovarian Function Of Women During The Reproductive Period

Objective:To observes the influences of uterine surgery on the ovarian function of women during the reproductive period.Methods:Subjects investigated were 180 female patients during the reproductive period, with reproductive system diseases requiring operation treatment. Operation schemes adopted cover various uterine surgery procedures including laparoscope and transabdominal approach, as well as myohysterectomy, supracervical hysterectomy, total hysterectomy (including extrafascial hysterectomy), and radical hysterectomy. FSH, E2, AMH are detected before the operation and redetected together with the symptoms of hot flashes 6 months after the operation.Result:Compared with preoperative detections, no patients experience any symptoms of ovarian failure. AMH in patients over 40 decreased remarkably 6 months after the operation. Little change (P=0.612) of AMH was detected in patients having received myohysterectomy, with (3.54±1.31)ng/ml before the operation and (3.69±1.35)ng/ml after. A slight decrease (P=0.598) of AMH was detected in patients with supracervical hysterectomy. A significant decrease (P<0.05) of AMH was detected in patients having received total hysterectomy (including extrafascial hysterectomy), with (1.80±0.96)ng/ml before the operation and (1.45±0.68)ng/ml after. A significant decrease (P<0.05) of AMH was detected in patients having received radical hysterectomy, with (3.31±0.92)ng/ml before the operation and (2.72±1.08)ng/ml after. A significant decrease (P<0.05) of AMH was detected in patients having received laparoscopic hysterectomy, with (1.94±1.10)ng/ml before the operation and (1.56±1.00)ng/ml after.Conclusion:Uterine surgery won’t cause ovarian function failure in the short term. Age, hysterectomy procedures and approaches may be the influential factors for a decline in ovarian reserve function in the short term.