Epidemiology Of Dyslipidemia In Adults In Gansu Province Of China

Aim: To determine the prevalence and risk factors of dyslipidemia among adults in Gansu province of China. Methods: Stratified, cluster and random sampling method was used to select a sample of 31417 participants of Han, Hui, Tibetan, Yugur, Dongxiang and Baoan ethnicity in Gansu, China. We measured the serum lipids(total cholesterol [TC], triglyceride [TG], high-density lipoprotein cholesterol [HDL-C], low density lipoprotein cholesterol [LDL-C]) concentrations in the subjects studied from 2013 to 2014. Results: The mean levels of TC, TG, LDL-C and HDL-C were 4.45, 1.74, 2.61 and 1.46 mmol/L, respectively. The prevalence of dyslipidemia was 37.9%. The age-adjusted prevalence of dyslipidemia was 36.8%. Of the participants studied, 6.1% had high TC, 22.1% had high TG, 4.0% had high LDL-C and 19.8% had low HDL-C levels. After standardization, the prevalence of high TC, high TG, high LDL-C and low HDL-C were 6.6%, 20.3%, 3.6% and 19.7%, respectively. The prevalence of dyslipidemia was higher among males than that among females(43.8% vs33.2%). Urban areas were more likely than rural areas to have a higher prevalence of dyslipidemia(40.6% vs34.8%). Racial disparity existed with the highest prevalence of dyslipidemia observed in Yugur(40.3%), lowest prevalence in Tibetan(25.8%). Binary logistic regression analysis demonstrated that dyslipidemia was significantly correlated with male gender, age, overweight, obesity, abdominal obesity, smoking, the family history of dyslipidemia, altitude, urban region,diabetes and hypertension. Conclusion: This study reveals a high prevalence rate of dyslipidemia in Gansu adults. The major types of dyslipidemia are low HDL-C and high TG. The rapid economy development and changes in dietary patterns may play an important role. An effective strategy is urgently required to prevent the epidemic of dyslipidemia in this area.