Discussing The Meaning Of Endoscopic Nasobiliary Drainage In The Prevention Of Post-ERCP Complications And The Drainage Time

Objective : To investigate the meaning of endoscopic nasobiliary drainage in the prevention of post-ERCP complications and the drainage time.Methods:Totally 2856 clinical data of ERCP cases,including 1902 patients with endoscopic nasal biliary drainage and 954 patients with no endoscopic nasal biliary drainage, were analyzed from 2004 to 2014. Meanwhile the 1902 patients with endoscopic nasal biliary drainage were divided into 1663 patients without pancreatitis nor cholangitis and 239 patients with either of them.Results:The incidence rate of hyperamylasemia and pancreatitis in the conventional ENBD group was significantly lower than the control group(19.18%vs48.00%, P<0.05; 2.76%vs8.38%, P<0.05).Also the incidence rate of acute cholangitis in the ENBD group and the control group is significantly different(1.02%vs4.61%,P<0.05). WBC and TBil could return to normal basically after nasobiliary drainage for 3 days in conventional group,which needed 5 days in Inflammation group.Conclusion:Endoscopic nasobiliary drainage can effectively prevent post-ERCP complications. Moreover,We suggest that nasobiliary duct should be placed for 3 to 5days.