| In recent years,China prevalence of type 2 diabetes(T2-DM) rose sharply in 1980 from 0.67%to 4%-5%in 2002,and will continue to increase,serious threat to the people’s life and health.Now the overwhelming majority of medical studies have shown that patients with T2-DM insulin resistance(IR).At present more than T2-DM treatment for hypoglycemic agents improve insulin-sensitizing agents such as TZD,in order to improve the IR.Chinese medicine from the overall concept,based on the Differential Treatment T2-IR DM patients with types of governance,reports have achieved a significant clinical effect.Objective:To investigate the Yiqiyangyin,Quyu Huatan method to improve Qiyinliangxu Syndrome,phlegm and blood stasis junction patients with type 2 diabetes the effect of insulin resistance,diabetes and its complications in order to reduce the incidence and mortality rates for new ideas and the method of treatment.Methods:According to 1999 WHO diagnostic criteria and standards of TCM,the choice of type 2 diabetes patients with insulin resistance in 60 cases,the treatment order were randomly divided into treatment and control groups.Treatment group(30 cases) diabetes therapy and traditional Chinese medicine decoction,the control group(30 cases) only to diabetes therapy.The period of treatment is one month.Main symptoms before and after the treatment of Chinese medicine points,fasting plasma glucose(FBG),2 hours postprandial blood glucose(PBG),fasting plasma insulin(FINS),hemorheology,lipids, and other indicators of change,and calculate insulin sensitivity index(ISI=1/FBG×FINS).At the same time also observed the changes of safety indicators such as blood,urine, liver and kidney functions,ECG in two groups before and after treatmentResults:①integral TCM symptoms after treatment group difference between statistical significance.②FBG,PBG,FINS,ISI have more significant difference(P＜0.05) in two groups,the difference compared FINS,ISI before and after treating has significant difference(P＜0.05),FBG,PBG no statistical difference(P＞0.05).③After treatment,lipids have significant difference(P＜0.05),no significant difference between the control group (P＞0.05),the difference between the two groups compared TC,TG,LDL-C has significant difference(P＜0.05).④After treatment,hemorheology changes are significant differences (P＜0.05),no significant difference between the control group(P＞0.05),the difference between the two groups compared HBV,LBV is a significant difference(P＜0.05).⑤before and after treatment,the two groups had no significant safety indicators changes in the course of treatment apparently.Conclusion:Yiqiyangyin,Quyu Huatan method has the role of improving Qiyinliangxu Syndrome,phlegm and blood stasis knot of Chinese patients with type 2 diabetes,lowering fasting insulin and increasing insulin sensitivity,lowering blood sugar,improving hyperlipidemia and high hemagglutinin,the Yiqiyangyin,Quyu Huatan method in the improvement of insulin resistance in type 2 diabetes has the potential space for development.In clinical application,and no Yiqiyangyin,Quyu Huatan Chinese medicine-related adverse events occurred,we can see that its clinical application is safe. |
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