Effects Of Motivational Interviewing On Medication Adherence Of Patients With Depression

Antidepressant drugs are the main method in the therapy of depression. The medication adherence is low in patients with depression, only 27% to 43%. It has plays an important role in therapeutic efficacy, financial burden, and quality of life of patients who suffer depression. There are many methods can influence the medication adherence, motivational interviewing included. It has been adapted to improve medication adherence in the past ten years, proving satisfying effects.Objective: To evaluate the effects of motivational interviewing in improving the medication adherence, beliefs about medication, and adherence confidence and motion in patients with depression.Methods: We recruit 160 patients of depression who were in psychiatry department one of the First Affiliated Hospital of Zhengzhou University. Patients were randomly assigned to two groups, intervention group(IG) and control group(CG). Normal information of two groups was collected by writing themselves or inquiring by investigator on baseline. Patients from CG received regular health education and We Chat/telephone follow-up. The other group not only received methods aboving, but also contained motivational interviewing. We would collect information of medication adherence, beliefs about medication, and adherence confidence and motion at baseline, one and three after discharge.Results: 144 patients were completed all data collection, 76 patients in IG and 68 patients in CG. There is no significant difference in normal information and clinical data between two groups. The results were:(1)The medication adherence of IG at one and three after dischargeis(78.95%,82.89%),which is higher than CG(33.82%,22.06%)(P<0.05). There is a significant difference between baseline and one and three after discharge in medication adherence of IG((MD=99.130,MD=107.596)P<0.05). but There is no significant difference in one and three after discharge(MD=0.384)(P>0.017).(2)Beliefs about medication in baseline(33.39±5.78) is markedly lower than that in discharge, one and three after discharge(43.64±3.11,46.80±3.35,44.91±5.93)in IG(P<0.008); And that is higher than that the beliefs about medication of CG at discharge, one and three after discharge(40.04±2.87,39.26±2.64,36.56±1.98)(P<0.05).(3)There is a significant difference between baseline(6.63±2.943,6.78±2.928)and discharge, and also between baseline and one and three after discharge in adherence confidence(9.03±0.966,9.14±0.795,9.20±0.895) and motion(9.09±1.035,9.25±0.954,9.49±0.721) of IG(P<0.08); The adherence confidence and motion of IG is markedly higher than CG at discharge, one and three after discharge(8.31±1.011, 8.09±1.047, 7.56±0.937; 8.34±0.956, 8.18±0.945, 7.87±0.96)(P<0.05).Conclusion:Motivational interviewing can raise medication adherence, beliefs about medication, and adherence confidence and motion, and lasting for at least three months.