Clinical Study Of Open Surgical Treatment Of Renal Primitive Neurotodermal Tumor With Tumor Thrombus In Inferior Vena Cava

ObjectiveKidney origin of primitive neuroectodermal tumors are relatively rare and extremely high degree of malignancy, PNET best treatment there is no clear conclusion. The incidence of kidney patients primitive neuroectodermal tumors are generally relatively late, and often inferior vena cava tumor thrombus consolidation under. This study was designed to investigate the transabdominal approach to surgical methods and efficacy of open surgery for kidney primitive neuroectodermal tumor with inferior vena cava tumor thrombus. Subjects and methodsThe clinical study data to select the First Affiliated Hospital of Zhengzhou University Urology admitted from January 2008 to January 2015 period rPNET merger IVC tumor thrombus in 7 patients. Including 3 males and 4 females; the left side of three cases of the disease, the right of the four cases of disease; patients aged 21 to 55 years, mean(33.9±21.1) years; maximum tumor diameter of 9.1 ~ 12.8 cm, the average(11.1±2.0) cm; vein thrombosis according to Mayo Clinic’s five-category classification methods: two cases of grade Ⅰ, Ⅱ grade 2 cases, 3 cases of grade Ⅲ; all patients by the same or similar surgical experience in the treatment group underwent open renal abdominal approach tumor radical resection of the inferior vena cava tumor thrombus removal surgery. Surgical time, blood loss, blood transfusion, intraoperative blocking blood flow, postoperative drainage tube pulled time, postoperative hospital stay, complications and prognosis, and clinical covariates were analyzed. ResultsIn this study, 7 patients were operated successfully completed, the operation time 190 ~ 255 min average(215.7 ± 39.3) min; blood loss was 400 ~ 600 ml, average(471.4 ± 128.6) ml; blood transfusion after 400 to 600, average(485.7 ± 114.3) ml; postoperative abdominal drainage tube removal time 4 ~ 6 d, the average(4.6 ± 1.4) d; postoperative hospital stay was 11 ~ 15 d, an average of(12.9 ± 2.1) d, 1 patient delayed wound healing, dressing after giving back to normal. 7 patients sustained postoperative follow-up, 2 patients died of tumor metastasis, 2 patients found that metastatic to the spleen, the remaining 3 patients were tumor-free survival, complications of liver and kidney function injury did not appear. ConclusionTransabdominal open surgical approach for the treatment of renal primitive neuroectodermal tumor with inferior vena cava tumor thrombus is a safe and feasible surgical options.