The Clinical Observation Of Shuganhewei Granules In The Treatment Of Chronic Atrophic Gastritis Qi Stagnation Syndrome Of Liver And Stomach

Research purposesObservation of clinical effect and mechanism of Shuganhewei granules of liver and stomach qi stagnation chronic atrophic gastritis, and an objective evaluation of its safety and effectiveness.Research ways Select the total 80 cases in Jinan City, Shandong Province Chinese Medicine Hospital of Digestive Diseases outpatient and inpatient CAG patients met the inclusion criteria, according to randomized double-blind controlled trial of standard subjects were divided into treatment group(Shugan group) and the control group(Weisu group of particles), two groups of 40 cases, treatment for 3 months. The treatment group received Shugan(drugs: Bupleurum, white peony root, Cyperus, Citrus aurantium bran fried, fried Atractylodes, Poria, Chuanxiong, Amomum, Gallus gallus vinegar, vinegar fumarate, fry six roses etc.), a daily morning and evening warm water; control group was given stomach Su granules, once 15 g, 3 times a day, warm water. The treatment lasted three months. Observe the two groups of patients before and after the treatment of clinical efficacy, traditional Chinese medicine syndrome curative effect, endoscopic pathology and HP eradication efficacy. Statistical software SPSS19.0 was used for statistical analysis of the relevant observation indicators.Research result 1.The total clinical efficacy compare two groups of patients: the treatment group, the total effective rate was 87.50% in the control group, the total effective rate was 57.50%. By statistical analysis, there are significant differences(P <0.05) of the total clinical efficacy of the two groups.2.The two groups of TCM syndrome comparison: the treatment group than the control group(P <0.05). Wherein the improvement epigastric fullness(or pain), flank pain unit, belching and other aspects of the treatment group is better than the control group(P <0.05 or P <0.01), in improving symptoms of chest discomfort was no obvious difference(P> 0.05).3. Comparison of the two groups of patients the efficacy of endoscopy: gastroscopy treatment group is better than the control group(P <0.05).4. Two groups of patients with histological efficacy comparison: the treatment group atrophy rate was 77.5%, 52.5% in the control group, the treatment group than the control group(P <0.05). No significant difference(P> 0.05) in the treatment of intestinal metaplasia and dysplasia groups.5. Comparison of the efficacy of the two groups of patients HP Clear: To the treatment group than the control group(P <0.05).6. Security rating: treatment group and control group had no significant adverse reactionsAnalysis conclusion Sparse liver and stomach particles liver qi stagnation stomach CAG patients have good clinical effect, it is an effective prescription treatment CAG liver and stomach qi stagnation, it is worth further promote the use of.