| Chronic heart failure(CHF)referred to heart failure.Is due to the structure of cardiac or functional disorders cause ventricular filling and ejection dysfunction,cardiac output quantity can’t meet the requirements of the body.With pulmonary circulation and/or circulation congestion,blood of organ and tissue hypoperfusion for clinical syndrome.Is the most of the terminal phase of the clinical manifestations of cardiovascular disease and one of the major cause of death.In recent years,Chinese medicine treatment of chronic heart failure has made great progress,In terms of control the symptoms and improve the life treatment and improve prognosis shows its unique advantages.This study through collect and collate the related literature of traditional Chinese medicine treatment of chronic heart failure,preliminary exploration of Chinese medicine dialectical medication rules for treating chronic heart failure,providing theoretical basis for the treatment of chronic heart failure and objective basis,in order to better guide clinical and research use.Objective: Through the analysis of traditional Chinese medicine treatment of chronic heart failure related literature research,and summarize the cardiac function of heart failure,the main primary disease,treatment,governing law and herbal prescription etc.To sum up,the preliminary exploration of chronic heart failure clinical dialectical law,providing theoretical basis for the treatment of chronic heart failure and objective basis,in order to better guide clinical and research use.Methods: Through retrieving China hownet Database search(China National Knowledge Infrastructure Database,CNKI),the Data resources of ten thousand system(Wanfang Data)and the VIP Database(VIP Chinese Science and Technology Periodical Database,VIP),with "heart","heart failure","cardiac insufficiency" as the "subject","essay","key words","from January 2005 to December 2005" as the literature published year,by downloading the literature citations,read the literature summary,when it is necessary to download the full text,selected into the standard literature,extract relevant information,including gender,cardiac function,the main primary disease,treatment,common witness,drug laws,drug kinds.Creating a database of traditional Chinese medicine treatment of chronic heart failure,based on the database using epidate and sorting,frequency of statistical methods to analyze the drug law of traditional Chinese medicine treatment of chronic heart failure.And using the basic theory of traditional Chinese medicine and illustrate the rationality of the medication rule of knowledge,providing theoretical basis for the treatment of chronic heart failure and objective basis,in order to better guide clinical and drug use.Results:1.This study summarized into standard of 546 articles,21336 cases with detailed gender data records are selected cases,10748 cases(about 50.4%)of men and women in 10588 cases(49.4%),the selected cases ratio close to 1 : 1.2.Through summarizing the literature of 546 Chinese medicine treatment of chronic heart failure,are selected with detailed data records of cases,15648 cases of primary disease,including coronary heart disease(CHD)in CHF various pathogenic factors in the first place,followed by high heart disease,rheumatic heart disease,lung,enlarge,etc.3.Collect nearly a decade of the 546 articles,have detailed data record,a total of 16432 cases of cardiac function classification of cases.Grade of cardiac function Ⅰ 219 cases(about 1.4%);Ⅱ level 4696(about 28.6%);Ⅲ level 7895(about 48.0%);Ⅳ level 3622(about 22.0%).4.The treatment of chronic heart failure often witness type preliminary identified as,sun be the spirit deficiency,blood stasis water stop qi deficiency,blood stasis,qi and Yin deficiency syndrome,qi and blood stasis,etc.The common treatment in patients with chronic heart failure is: the good temperature Yang,invigorate the circulation of the water line,yiqi huoxue,qi and nourishing Yin,invigorating qi and so on.5.Through the statistics found that the literature of 546 pieces of Chinese medicine treatment of CHF by the application of traditional Chinese medicine formulations(proprietary Chinese medicine and the quasi square)are classified,including proprietary Chinese medicine 280(about 58.1%),since the quasi square 266(about 48.7%).To specific drug category,the party applications,most of 266(about 48.7%),followed by intravenous agents,a total of 172(about 31.5%),oral literature at least,a total of 108(about 19.8%).Intravenous preparations of Chinese medicine treating CHF 172,intravenous preparation involves sort is more,a total of 13 species,to attach most injection application,a total of 40 papers(about 23.2%),followed by injection,a total of 39 articles(about 22.7%);Involved oral preparations 5 classes,most applications for qiliqiangxin capsule,a total of 60 papers(about 56.0%).6.Through statistical nearly 10 years 546 papers,Chinese medicine treatment of chronic heart failure involved drug kinds 20 classes,drug 150,number 2623.Medication types have a higher frequency of drugs in the first 10 drugs are: mend angry medicine,medicine for activating blood circulation and water permeability wet medicine,nourish the medicine,phlegm cough antiasthmatic,wen in medicine,blood tonic medicine,Yin medicine,heat medicine,facilitating medicine;The application medicine species with the highest frequency of drugs for invigorating qi,a total of 631(about 24.0%),use the lowest frequency for wet medicine and begin to understand medicine,each for five times(about 0.2%).Involved in 20 kinds of specific therapeutic agents in the treatment of chronic heart failure,drug use frequency and frequency of different drug kinds there is a difference.Mend angry medicine,astragalus membranaceus applied 176 times(about 27.9%),mainly including application 1 time(about 0.2%);Type of medicine for activating blood circulation and salvia miltiorrhiza used 160 times(about 34.7%),triangular,turmeric application 1 times each(each account for about 0.2%);The water moisture penetration medicine,poria cocos used 171 times(about 53.0%),winter melon kernel application 1 times(about 0.3%);Temperature in medicine in the application of lateral root of aconite 143 times(about 80.3%),Chinese prickly ash application 2 times(about 1.1%).7.Through the statistics of the literature of Chinese medicine treatment of CHF 546 papers found that the main drugs for the treatment of CHF are astragalus membranaceus,poria cocos,salvia miltiorrhiza,lateral root,ginseng,cassia twig,liquorice,atractylodes,tinglizi,alisma,rhizoma ligustici wallichii,angelica,radix ophiopogonis,safflower,red paeony root,schisandra fruit,etc.The commonly used drug combinations in the treatment of CHF,102 to 20 times more than common combinations,including astragalus membranaceus and salvia miltiorrhiza composite use frequency is highest,a total of 118 times,followed by astragalus membranaceus and poria cocos combination for 110 times,poria cocos and monkshood combination for 106 times,lateral root and atractylodes combination of 106 inferior.And tonifying qi,promoting blood circulation to remove blood stasis drugs,water pills moisture penetration,nourish,phlegm cough antiasthmatic,temperature in medicine,Yin drugs combined each other more.Conclusion:1.By defragmenting nearly 10 years of traditional Chinese medicine treatment of chronic heart failure of literature analysis,preliminary determine the type of chronic heart failure often witness in the order: sun be the spirit deficiency,blood stasis to stop water,followed by qi deficiency and blood stasis syndrome,qi and Yin deficiency syndrome,qi and blood stasis,etc.,and application of common treatment for chronic heart failure: good temperature Yang,invigorate the circulation of the water in the first place,followed by yiqi huoxue,qi and activating blood,etc.The type and chronic heart failure often witness basic is also relatively should be.2.The three categories of dosage forms of Chinese medicine,the treatment of chronic heart failure from party applications the most,followed by intravenous agents,oral preparations,least visible Chinese medicine medicinal broth occupies an important position in the treatment of chronic heart failure.3.Research shows that traditional Chinese medicine treatment of chronic heart failure involved drug kinds 20 categories,150 drug,has a wide range,both the relative concentration of a drug use frequency and frequency more mend angry medicine,such as astragalus,promoting blood circulation to remove blood stasis drugs such as salvia miltiorrhiza,water moisture penetration medicine such as poria cocos,also there is a relatively fragmented and drug use frequency and frequency less wet medicine such as cardamom,borneol resuscitation drugs.4.Main commonly used drugs for the treatment of chronic heart failure are astragalus membranaceus,poria cocos,salvia miltiorrhiza,aconite,ginseng,cassia twig,liquorice,atractylodes,tinglizi,alisma,rhizoma ligustici wallichii,angelica,radix ophiopogonis,safflower,red paeony root,schisandra fruit,etc.Astragalus membranaceus and salvia miltiorrhiza,astragalus membranaceus and poria cocos,poria and aconite,aconite and atractylodes,they has a relatively large number of drugs combinations.And tonifying qi,promoting blood circulation to remove blood stasis drugs,water pills moisture penetration,nourish,phlegm cough antiasthmatic,temperature in medicine,Yin drugs combined with more,this is also a concrete manifestation of heart failure syndromes and the rule of law. |
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