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Clinical Study Of Huoxue Zhitong Plaster To Treat Blood Type Bizu Disease

Posted on:2017-06-01Degree:MasterType:Thesis
Country:ChinaCandidate:F LiuFull Text:PDF
GTID:2334330512955402Subject:Fractures of TCM science
Abstract/Summary:PDF Full Text Request
Objective:Exploring the clinical treatment of osteoarthritis of the knee joint is an important issue at present. This topic through observating the clinical curative effect of Huoxue Zhitong plaster in the treatment of knee osteoarthritis and its related factors in human knee joint fluid index,thus providing more safe and effective Chinese medicine safe and effective application of traditional Chinese medicine to the treatment of knee osteoarthritis..Methods:This topic involved 44 cases of knee osteoarthritis patients, all patients diagnosed with knee joint fluid were taken after admission,used for testing of TNF-alpha, IL-6 levels by enzyme-linked immunosorbent assay (ELISA) to examine the content of TNF -? and IL-6, choose Shanghai Jiang Lai Biotechnology Co., Ltd. kit. The operation was carried out according to the operation kit manual. At the same time, the VAS score and the McMaster University Osteoarthritis Index (WOMAC) score were also given. Knee joint external Huoxue Zhitong plaster and then every 4 hours,1 times a day, after 2 weeks and 4 weeks treatment, with the same method review of TNF -?, IL-6 and retest scores of VAS and WOMAC. By observing the changes of VAS score, WOMAC score and serum TNF -?lpha and IL-6 value, from the clinical curative effect to explore the effect of Huoxue Zhitong plaster in the treatment of knee osteoarthritis.result:1. safety:Patients with a clinical trial due to skin allergies exit this clinical trial, the rest of the patients did not appear adverse reactions.2. Visual analogue scale (VAS) aspects:After topical Huoxue Zhitong ointment, compared with before treatment,42 patients with pain symptoms improved, medication 2 weeks, medication for 4 weeks before treatment and comparison exists there was statistically significant difference (P<0.05).3. Osteoarthritis Index (WOMAC):After topical Huoxue Zhitong ointment, compared with before treatment,42 patients with the WOMAC index decreased, medication 2 weeks, medication for 4 weeks before treatment and comparison exists there was statistically significant difference (P< 0.05).4. Biochemical indexes:After topical Huoxue Zhitong plaster,42 patients with serum TNF -? and IL-6 values than before treatment, medication 2 weeks, medication for 4 weeks before treatment and comparison exists there was statistically significant difference (P< 0.05).Conclusion:Huoxue Zhitong ointment is effective in relieving clinical symptoms such as knee osteoarthritis pain and so on, which can improve the function of knee joint, reduction of serum TNF -? and IL-6 levels, lower adverse reaction, less side effects, for the treatment of knee osteoarthritis is safe and feasible.
Keywords/Search Tags:Huoxue Zhitong plaster, knee osteoarthritis, blood stasis, clinical study
PDF Full Text Request
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