| Skin itchy is the most common symptoms of skin disease among the HIV/AIDS patients.It brings great suffering,increased psychological stress to the patients.Currently antihistamines including calcium-based formulation,calm stabilizers,vitamins etc are used clinically to control the itching,with glucocorticoid drugs if necessary.But as HIV/AIDS patients are very different from the status of the skin disease with common skin diseases,symptoms treated with these drugs is not obviously andrelieved has side effects.And antipruritic does not increase the patient medicine for external use only,safe,convenient.However at present,there are only a few such medicines and most of them are ineffective.Chinese medicine He-Qin antipruritic liniment comsists of by Hong geng,Yang he,Huang qin,etc,with detoxification,detumescence,moisture,and the effect of relieving itching,can quickly relieve itching symptoms of the patient in a relatively short time.This paper evaluated the He-Qin antipruritic liniment’s effect on on HIV/AIDS patients skin disease in clinic,And through the evaluation of the liniment of eosinophils in patients with plasma,CD4T lymphocytes and the role of IL-5 molecules.Preliminary explore its scientific basis for the treatment of skin itching from a cellular level and molecular level,aimed to scientifically prove itching effect,and to clarify its mechanism of action,Looking for a safe and effective treatment for clinical itchy skin disease of AIDS drugs,to provide practical and theoretical basis.Through the clinical curative effect observation and evaluation,the investigation of quality of life score,that external He-Qin antipruritic liniment can obviously improve clinical symptoms in patients with HIV/AIDS skin pruritus,and improve the quality of life;Laboratory studies indicate it can obviously reduce the patient’s eosinophil count,but cannot change patients CD4T lymphocytesdecrease and the content of plasma IL-5. |
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