The Clinical Research Of Traditional Chinese Medicine Combined With Exercise Therapy For The BMI And IR Index Of The Endomorphy Type Polycystic Ovary Syndrome

Objective: To observ the clinical curative effect of traditional Chinese medicine combined with exercise comprehensive therapy for fueling PCOS,especially for the influence of its BMI and IR index,and to explore the mechanism of the TCM of the yi-shen-xiao-zhi prescription preliminary,providing scientific basis of the clinical application for the prescription.Methods: 60 patients with endomorphy type PCOS were randomly divided into three groups A,B,C.A group of 30 cases,oral the yi-shen-xiao-zhi prescription combined with exercise therapy;B group of 30 cases,oral the yi-shen-xiao-zhi prescription and metformin;C group of 30 cases,oral the metformin combined with exercise therapy.After 3 course of treatment,observe the three groups of patients with improvement of clinical symptoms of TCM,the volumetric change of ovary,improvement of menstrual cycle,changes in the level of body mass index,luteinizing hormone,follicle-stimulating hormone,testosterone,LH/FSH,fasting plasma glucose,fasting insulin,homa-IR index,total cholesterol,triglyceride,high density lipoprotein cholesterol and low density lipoprotein cholesterol.Results:(1)In the aspect of improve TCM symptoms and the menstrual cycle,the curative effect of A group is superior to B,C groups significantly,the difference was statistically significant(P<0.05);and the curative effect of B and C groups were balanced,the difference was not statistically significant(P>0.05).In terms of changes in ovarian volume,three groups were not significantly reduced ovarian volume,the difference was not statistically significant(P>0.05).(2)In terms of reducing BMI,the curative effect of A group is superior to B,C groups,and C group is superior to B group,the difference was statistically significant(P<0.05).In terms of reducing fasting blood glucose and fasting insulin and insulin resistance,the curative effect of A group is superior to B,C groups,and B group is superior to C group,the difference was statistically significant(P<0.05).(3)In terms of reducing LH,T and LH/FSH,the curative effect of A group is superior to B,C groups,the difference was statistically significant(P<0.05);and the curative effect of B and C groups were balanced,the difference was not statistically significant(P>0.05).In terms of reducing the levels of TG,TC,LDL-C,the curative effect of A group is superior to B,C groups,the difference was statistically significant(P< 0.05);and the curative effect of B and C groups were balanced,the difference was not statistically significant(P>0.05).Conclusion: Traditional Chinese medicine combined with exercise therapy can improve the clinical symptoms of TCM of the endomorphy type PCOS,shorten the menstrual cycle,Improve ovulation;and can reduce the weight of patients,lower the BMI effectively;reduce the level of LH?T?LH/FSH?FPG?FINS?IR index?TC?TG and LDL-C,and improve the endocrine environment and the condition of glucolipid metabolism of the endomorphy type PCOS patients obviously,and change the constitution of kidney deficiency and phlegm stasis in PCOS patients,and the clinical curative effectively,it is worthy of popularization and Application.