| Background and ObjectiveTubal pregnancy refers to the embryo is in the fallopian tube,which is one of the most common form of ectopic pregnancy,which accounts for about 95 percent of ectopic pregnancies.Women who were pregnant with the tubal pregnancy was one of the most common diseases of fertility and life in women,it had a serious threat to the reproductive age.In clinical,tubal pregnancy was a disease that was not clear and the treatment plan was not completely unified.Clinical workers had never stopped studying it.In clinical trials,the pregnancy of the fallopian tube was diagnosed by the serum βHCG and the ultrasound of women.Serum beta HCG was produced by the synthesis of embryoblast cells,which may partly reflected the activity of the nourishing cells.Clinical trials of tubal pregnancy included drug therapy and surgical treatment,drug therapy was mainly applied to the use of chemotherapy drug methotrexate to suppress the proliferation of the nourishing cells and cause the embryo to die.Surgical treatment was cured by the removal of an oviduct pregnancy and the removal of the lateral fallopian tube.This topic was based on the analysis of the change trend and treatment outcome about serum βHCG before treatment.Materials and methods 1.MaterialsThe clinical data of 679 patients who were treated in the second affiliated hospital of Zhengzhou university from January 2012 to January 2016 were analyzed.2.MethodsStatistics all of the patients’ general information:age,pregnant times,production time,stop time,vaginal bleeding time,length of hospital stay and bag piece diameter size,the size of the concentration of serum βHCG before treatment.According to the treatment of the patients,there were 679 patients,including 265 in the drug treatment group(Group A),and 156 with single chemotherapy,109 cases of continuous chemotherapy.There were 414 cases of surgical treatment(Group B),272 in conservation operation and 142 in radical surgery.According to the changes in the serum beta HCG concentration in the patients treated,the rising group(group1)was 285 cases,the decline group(group2)was 188 cases.In group A,there were 100 cases with increasing trend,and 102 cases were decreased in group A2.Analysis of the results of treatment between these groups.ResultsOf the 679 patients,265 were conservative and 414 routine surgery.1.General informationIn age,pregnancy,menopause,and vaginal bleeding,group A and group B were non-statistical differences(P > 0.05).However,group A was hospitalized longer than group B;The attachment area of group A was smaller than group B,and group A was less than group B in the treatment of pre-treated serum βHCG.Group A and group B had statistical differences in these aspects.2.Case data(1)The success rate of single chemotherapy and continuous chemotherapy were 87.18%,91.74%,no statistical difference(P > 0.05)in the conservative treatment group(group A).(2)In the treatment of tubal pregnancy,the treatment success rate of group 1 was 88.77%,and the group 2 was 98.79%,the difference was statistically significant(P= 0.00< 0.05).The treatment success rate of group A1 and group A2 were 72.00%,99.02%,and statistical differences was significant(P = 0.00 < 0.05).Conclusion1.For patients with stable vital signs,the serum beta HCG of interval of 48 hours was increasing before treatment and was greater than five percent,the rate of failure of conservative treatment in drugs was higher.2.For patients with stable vital signs,the serum beta HCG of interval of 48 hours was decreasing before treatment and was greater than five percent,the rate of success of conservative treatment in drugs was higher. |