| Objective:On the basis of literature analysis and expert opinions,to find an application prescription for chronic gastritis qi stagnation syndrome,and to screen the appropriate acupoints,and then verify the clinical effect of acupoint sticking therapy in patients with chronic gastritis with qi stagnation pattern through rigorous scientific research design.Methods:Doing systematic review and meta analysis of acupoint application in the treatment of qi stagnation syndrome,and then using the Delphi expert consultation method,one formula was chosen from the nine recorded prescriptions and suggestions from the experts for epigastric pain patients with qi stagnation syndrome,considering the cost performaces,while acupuncture points were established by the content analysis and the law of acupoints chosen in the retrieved 306 articles with qi stagnation typed epigastric pain.Then clinical research was conducted on 90 cases of hospitalized patients with chronic gastritis of qi stagnation syndrome.They were divided into two groups,TCM acupoints sticking intervention group and placebo sticking intervention group,with 45 cases in each.After 14 days treatments,4 hours attaching each day,qi stagnation syndrome symptoms improvements were compared on every 0,3rd,7th,10th,14th day,while the total effects of symdromes of Chinese medicine,the quality of life of the patients,and the anxiety and depression scores were compared on every 0,7th,14th day.Results:1.Through the two rounds of expert consultation,it is proposed that the pastes are used to make Rhizoma Cyperi,Piper longum,Pericarpium citri reticulatae viride,Fried rhizoma corydalis,angelica dahurica and radix paeoniae alba in the proportion of 3:3:3:3:3:5,using water to reconcile.2.Through content analysis,we find the most common sticking points are:Chungwan(CV 12),Shenque(CV 8),double Tsusanli(ST 36),double Pishu(BL 20),double Weishu(BL 21)and double Kanshu(BL 18)points.3.A total of 90 hospitalized patients were enrolled in the clinical trial,and 4 patients were excluded.Finally,44 patients in the intervation group and 42 patients in the control group were included.Before intervention,there was no significant difference in baseline data between the two groups(P>0.05).After the intervention:3.1 The clinical effect of qi stagnation syndrome:between the two groups,the total grading score of qi stagnation syndrome and the overall symptom efficacy of TCM were statistically significant on 7th,10th days(P<0.05).The repeated measures ANOVA analysis on 0,3rd,7th day showed statistically significant difference in time effect(P<0.001),and there was an interaction effect between intervention and time factors(P<0.001).The dimensions of abdominal distension and poor appetite of qi stagnation pattern improved significantly in the intervention group(P<0.05),and there was no statistical significance of epigastric pain,belching,angrily,sighing,chest tightness,and regurgitation dimension between the two groups(P>0.05).3.2 The quality of life of chronic gastritis:between the two groups,there was no significant difference in the total score of the QOL scale after 7 days of intervention(P>0.05),and the difference of the specific module dimension related to the symptoms of gastritis was statistically significant(P<0.05),while there was no significant difference in the physiological function,psychological function and social function dimensions(P>0.05).After hospitalized for 7 days,the total score of quality of life scale of the total 86 patients increased significantly(P<0.001).3.3 The state of anxiety and depression:between the two groups,there was no significant difference in the score of Zung anxiety and depression scores after 7 days of intervention(P>0.05).The improvement of anxiety in 86 patients before and after hospitalization was statistically significant(P<0.05),but the improvement of depression has no statistically difference(P>0.05).The level of anxiety and depression of chronic gastritis with qi stagnation pattern were higher than the domestic norm scores.Conclusion:1.The Delphi expert consultation method can be used as an effective integrated research method to resolve different opinions in the field of TCM treatment and nursing.2.On the basis of meridians and collaterals theory,literature retrieval and content analysis can be used to find some specific rules in a scientific way,which can help selecting targeted acupoints to improve the curative effect.3.Chinese medicine acupoint sticking therapy is helpful to improve the symptoms of chronic gastritis with qi stagnation syndrome,such as abdominal distention and poor appetite,and improve the quality of life at the same time.Because of its easy operating and low cost,it is suitable for clinical and family application.4.The level of anxiety and depression in the chronic gastritis with qi stagnation syndrome is obviously higher than that of the domestic norm.This group of people needs to be paid attention to and guided properly in order to promote their recovery and improve their quality of life. |
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