The Effect Of Different Exercise Intensity On The Cardiovascular Events And Its Risk Factors In Phlegm Dampness Elderly Patients With Isolated Systolic Hypertension

Objective:The aim of this study was to explore the effect of low and moderate intensity exercise on the cardiovascular events and risk factors in phlegm dampness elderly patients with isolated systolic hypertension,and to determine the suitable exercise intensity for the elderly.Methods:This study adopted strict randomized controlled design to evaluate the effect of fast walking with low and moderate intensity.The participants of this studies were phlegm dampness elderly population with isolated systolic hypertension.A total of 211 participants were randomly allocated into 50%maximum heart rate of low intensity exercise group(n=72),70%maximum heart rate of moderated exercise intensity group(n=69)and physical activity control group(n=70).The three groups both received antihypertension drugs as basic treatment,low and moderated exercise groups performed 3 times per week,60 minutes each time(reach target heart rate for 30 minutes),lasting six months.The control group kept the original way of lifestyle.Before and after intervention,vascular function(ankle brachial index,pulse wave velocity),blood pressure,blood pressure variability(24hSSD and 24hDSD),Homocysteine,blood glucose(fasting blood glucose,glycated hemoglobin),blood lipid(total cholesterol,triglycerides,low density lipoprotein Cholesterol,high density lipoprotein cholesterol),body mass index,waist-to-hip ratio and phlegm dampness constitution score are detected.At the same time,cardiovascular events were collected.To evaluation of the possible influence of 6 months of regular exercise on cardiovascular events and risk factors in phlegm dampness elderly patients with isolated systolic hypertension.Results:1.Compared with the control group,the ankle brachial index and high density lipoprotein cholesterol increased in the low and moderate intensity group after intervention(P<0.05),and pulse wave velocity,total cholesterol,triglycerides,low density lipoprotein cholesterol and phlegm dampness constitution scores are all decreased(P<0.05).The elevation and the reduction are greater in moderate intensity group than the low intensity group(P<0.05);2.Compared with the control group,systolic blood pressure decreased after the intervention between low and moderate intensity groups,and there is no significant difference between the low and moderate group(P>0.05);3.There is no significant difference of diastolic blood pressure,blood pressure variability,body mass index,waist-to-hip ratio,fasting blood glucose,glycated hemoglobin and homocysteine between the low intensity,moderated intensity and control group(P>0.05);4.By collecting the occurrence of cardiovascular events during the 6 months of intervention period,it can be observed that the incidence of cardiovascular events in the moderate intensity group is falling blow than that in the low intensity and control group,but there have no significant difference in cardiovascular events between the three groups(P>0.05).Conclusions:1.6 months of low and moderate intensity of walking both could improve the vascular function,phlegm dampness constitution score and blood lipids for elderly isolated systolic hypertension patients,and the moderate intensity is better than that in the low intensity.2.6 months of low and moderate intensity of walking could further reduce the systolic blood pressure for the elderly isolated systolic hypertension patients even the blood pressure is reach the target one.3.6 months of moderate intensity of walking probably could reduce the incidence of cardiovascular events in elderly isolated systolic hypertension patients,which may be related to the improvement of vascular function and the control of some risk factors.