Objective:Observation and comparison of acupoint catgut embedding therapy wit h filiform needle acupuncture in the treatment of liver stagnation and sple en deficiency type chronic fatigue comprehensive syndrome clinical curativ e effect and function characteristics, and to explore its possible mechanis m, and provide objective basis for clinical application.Method:Will meet the inclusion criteria of 60 patients were randomly dividedinto A group and B group, 30 cases in each.A group was treated with ac upoint catgut embedding therapy, group B with acupuncture treatment.Gans hu, Zusanli, Geshu acupoint were selected for the first group,Pi Yu, Sanyi njiao, Danshu for second points, two groups alternate application.A group every 10 days buried 1 times, a total of 4 treatments; B group treated for8 days, 2 days off for 1 cycles, 4 cycles of treatment.At before and afte r treatment,Fatigue Scale(FS-14) and Fatigue Symptom Score Scale and th e Liver Stagnation and Spleen Deficiency Syndrome Score Scale were use d to evaluate respectively on three subjective indicators of the main sympt oms of fatigue,fatigue associated symptoms and traditional chinese medicin e Syndrome;And venous blood was extracted and the cortisol levels in per ipheral blood serum of two groups were detected by chemiluminescence m ethod.Result:1.After treatment, the two groups of patients with FS-14 scores than before treatment were significantly decreased, the difference was statisticall y significant(P<0.01); A group than the B group decreased more, the diff erence was statistically significant(P<0.05).2.After treatment, the two groups of patients with fatigue symptom scores than before treatment were significantly decreased, the difference wasstatistically significant(P<0.01);but there was no significant difference be tween the two groups after treatment(P>0.05).3.After treatment, the two groups of patients with liver stagnation andspleen deficiency syndrome score before treatment were significantly decr eased, the difference is significant(P<0.01); but the difference between th e two groups no significant(P>0.05).4.After treatment, the Overall response was no significant difference b etween the two groups(P>0.05).5.After treatment, the content of cortisol in the two groups was signif icantly higher than before treatment, the difference was statistically signifi cant(P<0.01); the difference between the two groups was not significant,and there was no statistical significance(P>0.05).Conclusion:Catgut implantation at acupoint and acupuncture needle puncture in th e treatment of liver stagnation and spleen deficiency type CFS has obviou s effect, can significantly improve the patient fatigue symptom and syndro me of liver stagnation and spleen deficiency symptoms, but acupoint catgu t embedding therapy on improving the main symptoms of fatigue have obv ious advantages, and a small number of treatments, low time cost, clinical can be preferred. At the same time, both of which can obviously increas e the content of cortisol in serum of patients with stagnation of the liver and deficiency of the spleen syndrome CFS that its mechanism of action i s likely to improve the neuroendocrine system in the HPA axis function h as the close relation, worthy of further study. |