Literature Analysis Of Chinese Medicine Treatment Of Luteal Insufficiency Infertility And Summary Of Professor Zhao Hong's Medication Rules

Luteal phase defect(LPD)was proposed by Jones in 1949.It refers to the hypoplasia of the corpus luteum after ovulation,premature degeneration,incompleteatrophy,lack of progesterone secretion,and endometrial dyssecretion.Menstrual disorders and fertility Functional defect syndrome.With the opening of the second-child policy,many pregnant women and mothers have joined pregnant women.The incidence of luteal insufficiency in infertility patients has increased accordingly.In recent years,Chinese medicine has made some progress in the treatment of infertility due to luteal incompetence,but most medical practitioners use experience or self-prescription to treat it.There is no law in the prescription for medication.Therefore,this topic adopts the method of data mining literature,sums up and summarizes the experience of the domestic doctors in the treatment of luteal insufficiency infertility in the past 20 years,and analyzes the medication laws.The tutor is now the Chief Physician of TCM Gynecology,Master's tutor,engaged in the clinical,scientific research and teaching work of TCM gynecology for more than 30 years.He has rich clinical experience and unique understanding of the diagnosis and treatment of infertility,so the tutor treatment of luteal insufficiency is not The experience of pregnancy is summarized and inherited.Research purposes:Based on the " Traditional Chinese Medicine Inheritance Support System(V2.5)" software to analyze the prescriptions of the domestically published literature on the treatment of corpora luteum incompetence infertility group,excavate the frequency of drugs in the prescription,four gas five flavor,drug return,the commonly used Drug pairs,core combinations,and new combinations provide ideas and lessons for clinical treatment.At the same time,they collect and record clinical information and prescription medications for patients with luteal incomplete infertility at the outpatient clinic of the mentor.The "Traditional Chinese Medicine Inheritance Support System(V2.5)" software is used for statistics and induction,and summarizes the experience of the tutor in using the traditional Chinese medicine to treat the disease.Research Methods:The study is divided into two parts:Part I:Searching formulas for the treatment of infertility caused by luteal incompetence in the literature published in the past 20 years,inputting the Traditional Chinese Medicine Inheritance Support System(V2.5),and statistically analyzing the frequency of Chinese herbal medicines composed of prescriptions.Drug compatibility combination,drug relevance,and summarization of core drug combinations and new party analysis based on data results;Part II:Collection of data and prescriptions for patients with luteal incompetence infertility that meets the inclusion criteria in the outpatient clinics,and input into Traditional Chinese Medicine Inheritance Support System,statistical analysis of patient basic information,frequency of medication,four gas five flavors,drug narcosis,common drug combinations,core combinations,and new mining.Research results:(1)Literature research:The 104 prescriptions that meet the inclusion criteria in the literature were entered into the Traditional Chinese Medicine Inheritance Support System for statistical analysis.A total of 18 herbal medicines with a frequency of more than 20%were used,followed by Dodder,Angelica,and Rehmannia in order of frequency of occurrence.Yellow,white peony,wolfberry fruit,Epimedium,Cyperus rotundus,yam,hawthorn,Dipsacus,Ligustrum lucidum,Bupleurum,Salvia miltiorrhiza,Radix paeoniae Rubra,Cistanche deserticola,Poria cocos,and licorice.The statistical results of four gas and five flavors of traditional Chinese medicine suggest that warm and peaceful Chinese medicines have a high proportion,and the proportion of Chinese medicines with sweet and spicy tastes is high.Analyze the prescription of the group,set the support to 30%,and the highest frequency of drug combinations is 17 groups,including 9 Chinese herbs,set the confidence level to 0.75,analyze the drug combination obtained above,and obtain the commonly used drugs.Combination of network display:Rehmannia-Angelica-Angelica-Dodder-Hawthorn-Gardenia-Epimedium-Dipsacus-Cyperus rotundus.(2)Clinical study:25 outpatients with luteal insufficiency who met the inclusion criteria were collected in the outpatient department,totaling 125 patients and 125 prescriptions.The most frequently used ten taste drugs used by the tutor outpatients for the treatment of luteal insufficiency in infertility were:white peony,dodder seed,wolfberry fruit,Huangjing,donkey-hide gelatin,angelica,Morinda-officinalis,Ligustrum lucidum,Chinese yam,and Huangqi.The use of traditional Chinese medicine in the four gas statistics,the most common application of warm medicine,followed by a flat drug,cold drugs less applied,cool and hot Chinese medicine is the least.The statistics of five flavors and the application of sweet Chinese herbs are the most,followed by the pungent,bitter,and sour tastes,and the application of astringent and salty Chinese herbs is the least.According to statistics,the traditional Chinese medicine belonging to the liver has been used most frequently,followed by the kidney and spleen,followed by the lung,heart,and stomach meridians.Research conclusions:1 In the literature research part,through the statistical analysis of the traditional Chinese medicine prescriptions for the treatment of LPD infertility in the literature for the past 20 years,it has been concluded that the menstruation medication is mainly used to promote blood circulation and qi;and the follicular phase is mainly used to supplement liver and kidney medicines.Ovulation medication to relieve liver qi,nourishing and activating blood circulation drugs;luteus phase of medication to warm kidney yang,nourish Yin blood.As a whole,the use of drugs to benefit liver and kidney,nourishing the liver to promote blood circulation.2 In the clinical research part,through the statistical analysis of the prescriptions of Chinese herbalists for the treatment of LPD infertility,Dr.Zhao Hong used to treat the disease to nourish the liver and kidney,warm the kidney and spleen,supplement Qi and nourish blood,supplement with diverting liver qi and promoting blood circulation.