Clinical Study Of Sticking On Shenque Point With Traditional Chinese Medicine To Treat The Cancer Pain

1 ObjectiveThis is a subject that sticking on shenque point with TCM to treat the cancer pain as a breakthrough point.Explore the feasibility of sticking on shenque point with TCM combined with three ladder analgesic drugs in the treatment of cancer pain,and compared with the three ladder analgesic drugs,whether it has analgesic effect,increase the degree of pain relief,reduce the side effects of analgesic drugs and improve the quality of life of patients.In order to provide the basis for TCM treatment of cancer pain.2 Methods60 patients with malignant tumor accompany cancer pain were randomly divided into observation group(n=30)and control group(n=30).The control group was given oral medicine according to the principle of WHO three step analgesic.The observation group was treated with sticking on shenque point with TCM on the basis of the control group.We observed 7 days and then compared the analgesic effect,the average analgesic onset time,the maintenance time,the NRS score,the times of breakout pain the quality of life and adverse reactions of the two groups.3 Results3.1 Baseline comparison between the two groups:No significant differences between two groups in age,gender,disease,clinical stage,previous treatment,pain degree,KPS score,QOL score etc.The two sets of data are comparable.3.2 Comparison of the degree of pain relief:The rate of pain relief in the control group was 73.3% after treatment,the rate of pain relief in the observation group was 80.0%after treatment.The pain relief rate was higher in the observation group than in the control group,but the difference was not statistically significant.3.3 Comparison of the NRS score:The score of NRS in the control group was 2.93±0.98,the score of NRS in the observation group was2.60±0.968.The score of NRS of the control group was higher than that of the observation group,but the difference was not statistically significant.3.4 Comparison of the onset time and duration of analgesic drugs:The onset time of the control group was 27.10±4.00(min),and the duration was 4.64±1.53(h).The onset time of the observation group was 25.03±4.27(min),and the duration was 5.05±1.31(h).The onset time of the observation group was short and the duration was long.The difference between the two groups was not statistically significant.3.5 Comparison of the times of breakout pain:The times of breakout pain in the control group was 1.93±0.73(Time).The times of breakout pain in the observation group was1.66±0.71(time).The times of breakout pain of the observation group was less than that of the control group,the difference between the two groups was not statistically significant.3.6 Comparison of the score of KPS : The score of KPS in the control group was69.33±6.91(score).The score of KPS in the observation group was 74.00±10.37(score).The score of KPS of the observation group was higher than that of the control group,the difference between the two groups was statistically significant.3.7 Comparison of the score of QOL:In the control group,the QOL score was increased in 10 cases,stabled in 15 cases and reduced in 5 cases.In the observation group,the QOL score was increased in 18 cases,stabled in 11 cases and reduced in 1 cases.The score of QOL of the observation group was higher than that of the control group,the difference between the two groups was statistically significant.3.8 Comparison of the security:The adverse reactions of the control group were more than those in the observation group,and the difference in the incidence of nausea and vomiting and constipation was statistically significant.There were no obvious abnormal changes in blood,urine,fecal routine,liver and kidney function,electrocardiogram andso on in the two groups of cases.The patients in the observation group had no obvious skin redness,pain and ulceration during the treatment of the umbilicus.4 ConclusionBy comparing the two groups of patients before and after treatment of the degree of pain relief,NRS score,onset time and duration of analgesic drugs,times of breakout pain,adverse drug reaction,safety index,KPS score and QOL score etc,found that sticking on shenque point with TCM combined with The drugs of three-step analgesic has a certain synergistic effect for relieving cancer pain.Sticking on shenque point with TCM combined with the drugs of three-step analgesic compared with only simple Three staircase analgesic drugs,it can reduce the side effects of opioids,such as nausea and vomiting,constipation,dizziness and so on,and it can also improve the quality of life of patients.