Simultaneously Liver Metastasis Of Colon Cancer In Clinical Risk Factors Analysis

Objective: To explore the clinical risk factors of colon cancer with simultaneous liver metastasis and to improve early diagnosis and improve prognosis.Method: We retrospectively analyze the clinical data of the 2297 patients with colon cancer,who have been hospitalized and surgicaled in the our hospital from the January 2013 to January 2017.Through data retrieval,60 colon cancer simultaneous liver metastasis who has data integrity were found.By means of the predisposition score matching method,the gender and age were matched in the database except 60 cases,and 120 patients with intact primary colon cancer were matched with 1:2.Our clinical data on colon cancer patients in this study were: gender,age,past history(hypertension,diabetes);Clinical manifestations(intestinal obstruction,ascites,colon polyps,cirrhosis,fatty liver);Blood biochemical examination(liver function,hepatitis,kidney function,hemoglobin,tumor series);Pathology(tumor site,general type,tumor type,number of lymph node metastasis,differentiation degree,infiltration depth)of the following factors may influence spread to the liver,such as covariate,according to whether with liver metastasis was divided into two groups,and then the single factor and multiple factors analysis,finally it is concluded that the related risk factors for patients with liver metastases from colon cancer.Results: Single factor analysis showed that colon cancer and liver metastasis related risk factors are: the colon polyp,fatty liver,ALT,AST,CEA and CA199,preoperative tumor site,gross type,tumor size,number,number of positive lymph nodes and lymph node cleaning.Multivariate Logistic regression analysis: CEA,tumor site,general type,lymph node dissection number is an independent risk factor for liver metastasis of colon cancer.Conclusion: Clinical risk factors of colorectal cancer with simultaneous liver metastasis are as follows: CEA,tumor site,macroscopic type and lymph node dissection number.