Study On Blood Routine Related Indicators And Clinical Value Of Procalcitonin In Bloodstream Infection

Objective: To investigate the clinical value of procalcitonin,white blood cell count,percentage of neutrophils,percentage of lymphocytes,neutrophil to lymphocyte ratio,platelet count and its parameters in the diagnosis and efficacy evaluation of bloodstream infection.Methods: A total of 111 patients with blood-positive bloodstream infections from January 1,2016 to December 1,2018 were selected as the experimental group,including 50 Gram-positive bacteria infections and 61 Gram-negative bacterial infections.Another 56 patients with non-bloodstream infection were selected as the control group.The blood routine related indicators and the difference of procalcitonin in the bloodstream infection group and the non-bloodstream infection group were compared.Results: In addition to the mean platelet volume,white blood cell count,neutrophil percentage,lymphocyte percentage,neutrophil to lymphocyte ratio,platelet count,platelet specific volume,platelet volume distribution width,and calcium reduction were observed in the bloodstream infection group.The prostagnation was significantly higher than the non-bloodstream infection group,and the difference was statistically significant(P<0.05).However,in thecomparison between Gram-positive bacteria and Gram-negative bacteria infection group,only the mean difference of neutrophil-lymphocyte ratio was statistically significant(P<0.05).Further ROC curve analysis showed that the diagnostic efficiency of blood flow infection from high to low was neutrophil to lymphocyte ratio,neutrophil percentage,procalcitonin,platelet volume distribution width,white blood cell count,Platelet specific volume,platelet count,and percentage of lymphocytes.The AUC of neutrophil to lymphocyte ratio was 0.756,and the sensitivity was 76.40% and specificity was 73.20%when the cutoff value was 6.322.The ratio of neutrophil to lymphocyte in the Gram-negative bacterial infection group was significantly higher than that of Gram-positive bacteria.When the cut-off value was 7.666,the sensitivity was80.40% and the specificity was 48.00%.In the bloodstream infection group,the results of the above indicators were re-examined after 72 hours of treatment,except for the average platelet volume,neutrophil to lymphocyte ratio,white blood cell count,neutrophil percentage,lymphocyte percentage,platelet count There were significant differences in the count,platelet volume distribution width,platelet specific volume,and procalcitonin before treatment(P<0.05).In the non-bloodstream infection group,after the treatment of body temperature returned to normal 72 hours later,the above indicators and poor prognosis were reviewed.Before the discharge,the above indicators of inflammation were statistically analyzed.There was no significant difference between the two indicators before and after treatment(P>0.05).Conclusion: Neutrophil to lymphocyte ratio(NLR),white blood cell count,neutrophil percentage,lymphocyte percentage,platelet count,platelet volume distribution width,platelet specific volume,procalcitonin in predicting bloodstream infection Diagnostic value.Mean platelet volume(MPV)is of littlevalue in identifying bloodstream infections and non-bloodstream infections.NLR is the most important indicator of infection in bloodstream infections and helps distinguish the type of bloodstream infection.When the bloodstream infection occurs,the NLR increases.When the index is greater than the cutoff value of 6.322,it can assist in the identification of bloodstream infection and non-bloodstream infection.When the value is greater than the cutoff value of7.666,it can be assisted to identify Gram-negative infection.And its cost is low,the detection is stable,and it has unique advantages.