The Clinical Observation On Dermatitis Detoxification Decoction Treatment For Yin Deficiency And Heat Syndrome Of Facial Hormone-Dependent Dermatitis

Objective:By observing the clinical effect of dermatitis detoxification decoction in treatment of facial hormone-dependent dermatitis with yin deficiency and heat syndrome,we explore the feasibility of the theory of “ release of fire stagnation” in the treatment of facial hormone-dependent dermatitis.It provides new treatment ideas and theoretical basis for treating facial hormone-dependent dermatitis.Methods:In this research,60 patients with facial hormone-dependent dermatitis were selected and randomly divided into 2 groups.The treatment group used dermatitis detoxification decoction combined with Lanrun medical healing skin biofilm,the control group was treated with compound glycyrrhizic acid glycosides tablets combined with Lanrun medical healing skin biofilm.Four weeks is a course of treatment,observe the therapeutic effect after a course.The general date of sex,age and course of the subjects were statistically treated before the test,and the results showed no significant difference.After the treatment,the scores were calculated according to the score scale,and statistical treatment was performed to analyze the clinical efficacy.Results:1.Before treatment,the score of sex,age,course of disease,subjective and objective symptoms and comprehensive integration were compared,P > 0.05,the difference was not statistically significant,indicating that the two groups were comparable.2.The two groups were compared in the group of subjective and objective symptoms before and after treatment,and obtained P < 0.05,the difference was statistically significant,which showed that both groups had improved in both the subjective and objective symptoms.The comparison between the two groups of patients with subjective symptom scores after treatment showed that P >0.05 was not statistically significant,indicating that the improvement of subjective symptoms in the treatment group was no different from that of the control group.The comparison between the two groups after treatment of objective symptom scores showed that P < 0.05,and the difference was statistically significant,indicating that the objective symptoms of the treatment group were significantly improved compared with the control group.3.In the improvement of symptoms and signs,both groups had improved symptoms.There was no significant difference between the treatment group and the control group in the improvement of subjective symptoms.In terms of objective symptoms improvement,the treatment group in erythema,papules,desquamation and telangiectasis obviously improved compared with control group,while in swelling,pigmentation,epidermal atrophy are no significant differences.4.In terms of safety,the treatment group showed mild diarrhea,stomach discomfort,and ordered a small amount of warm clothing after the meal,and then the symptoms were relieved.At the end of the course of treatment,the patient’s vital signs were normal,and no obvious abnormalities were found in blood routine examination,urine routine test,liver function examination and serum electrolyte examination.5.In the recurrence of the disease,3 months follow-up after treatment,the treatment group recurrence rate was 11.54%,the control group recurrence rate was 52.38%,P < 0.05,the difference was statistically significant,indicating that the treatment group recurrence rate is lower than the control group.Conclusion:The symptoms and signs of the two groups were improved after treatment.The two groups were equally effective in improving the subjective symptoms of pruritus,burning,and drying.The treatment group was superior to the control group in improving the objective symptoms of erythema,papules,desquamation and telangiectasis..But for improving the swelling,pigmentation,epidermal atrophy and other objective symptoms,there is no significant difference between the treatment group and the control group.Although there were differences in the two groups after treatment,the symptoms and signs showed improvement,but the improvement was more obvious in the treatment group than in the control group.The recurrence rate in the treatment group was lower than that in the control group.After comprehensive comparison,the treatment group was more effective than the control group.The effect was comparable with the control group in improving subjective symptoms,but it was better than the control group in improving some objective symptoms,and the treatment group recurrence rate was low.This result may contribute to the study of the treatment of facial hormone-dependent dermatitis,suggesting that the theory of “ release of fire stagnation” is meaningful in the treatment of the disease.It also provides a new treatment idea and theoretical basis for Chinese traditional medical treatment of facial hormone-dependent dermatitis.