| Objective:To discuss the clinical effect and safety of sufei xiaofeng runzao prescription for treating wind-induced pulmonary injury of cough variant asthma(CVA).Methods:In this study,60 cases of CVA patients aged 18-65 years with syndrome differentiation of wind drabness and lung injury who met the inclusion criteria were collected.According to the design scheme of clinical randomized controlled trial,patients were divided into two groups by random number table method,including 30 cases in the control group and 30 cases in the observation group.The control group was treated with conventional western medicine(budesonide formoterol inhalation 160ug/4.5ug/suction,one in the moming and one in the evening),while the observation group was treated with sufei xiaofeng runzao prescription.The observation period of both groups was 4 weeks and follow-up was 2 months.Data of the two groups of patients before and after treatment were collected,and indicators such as visual simulation score,cough score scale,LCQ questionnaire for cough quality of life(LCQ)and TCM syndrome score were recorded.Finally,statistical analysis was carried out to explore the efficacy and safety of xufei xiaofeng runzao prescription for patients with cough variant asthma with wind and dryness injury to the lung.Results:1.Visual analogue scoring(VAS):the difference before and after treatment was statistically significant(P<0.05),and the difference before treatment was greater than that after treatment.There was no significant difference between groups before and after treatment(P>0.05).2.Cough score:the difference between the two groups before and after treatment was statistically significant(P<0.05),and the difference before and after treatment was greater than that after treatment.There was no statistically significant difference between the two groups before and after treatment(P>0.05).3.Comparison of LCQ score:the difference before and after treatment was statistically sigriificant(P<0.05),and the difference after treatment was smaller than that before treatment.After treatment,the difference between the two groups was statistically significant(P<0.05),and the experimental group was significantly higher than the control group.4.Curative effect of TCM syndrome points;the intra-group comparison showed statistical significance before and after treatment(P<0.05),and the value before treatment was greater than that after treatment.There was no significant difference between the two groups before and after treatment(P>0.05).5.Recurrence rate:the difference was statistically significant(P<0.05),and the recurrence rate in the control group was significantly higher than that in the experimental group,6.After the investigation of the causes of recurrenee in this study,it was found that cold,allergen contact(pollen,animal dander,etc.)and house decoration were some important triggers for patients with recurrent CVA.Therefore,precautions and management should be taken during the treatment of the disease.Conclusion:1.The clinical efficacy of xuefeng xiaofeng runzao recipe in the treatment of cough variant asthma(lung type caused by wind dryness)is equivalent to thatof budesonide formoterol inhalation once in the morning and once in the evening.2.In terms of improving the quality of life,the observation group of sufei xiaofengrunzao prescription has more advantages than the control group.3.In the short-term follow-up,sufei xiao feng runzao prescription can botter control the recurrence rate. |