| Objective: the purpose of this study is to study the improvement of cough symptoms in wind-dryness lung type cough variant asthma by external application of Maiju Fangfeng plaster on the basis of conventional inhalation drugs.to observe the clinical effect of this therapy on cough variant asthma of wind-dryness injury lung type,in order to provide theoretical guidance and experimental basis for clinical application.Methods: In this study,98 patients who met the inclusion criteria in the respiratory clinic and ward of Qinhuangdao traditional Chinese Medicine Hospital from October 2021 to October 2022 were collected.The98 patients were randomly divided into control group and treatment group.There were 49 patients in each group.The control group was treated with routine western medicine,specifically referring to the routine treatment of bronchial asthma,including getting out of the sensitized environment,quitting smoking,inhaling budesonide formoterol,once a time,twice a day,once in the morning and evening;on the basis of the control group,the treatment group was treated with Mai Ju Fangfeng paste on Shuangdingchuan,Shuangfeishu and Xianwei points,daily before going to bed,torn off after 8 hours,and treated for 3 weeks.All the drugs involved in the observation were provided by Zhongcheng Western Pharmacy and Herbal Pharmacy of Qinhuangdao traditional Chinese Medicine Hospital.The pulmonary function(FEV1%)and the percentage of peripheral blood eosinophils were recorded before and after the end of the third week of treatment.Cough symptom score,cough VAS score,cough quality of life score and TCM clinical symptom score(cough,pharynx itching)were recorded before the beginning of treatment,after the end of the second week and the end of the third week.The above data were analyzed by statistical software SPSS26.0.To evaluate the efficacy of Maiju Fangfeng paste in the treatment of cough variant asthma of wind-dryness injury lung type.Result:1.FEV1% comparison: after 3 weeks of treatment,there was significant difference between the two groups in FEV1% group(P < 0 01),and after 3 weeks of treatment,there was significant difference between the two groups(P < 0 01).2.EOS% comparison: after 3 weeks of treatment,there was significant difference between the two groups in EOS% group(P< 0 01),but there was no significant difference between the two groups after 3 weeks of treatment(P > 0 05).3.Comparison of cough scores: at the end of the second week of treatment,there was significant difference in the daytime cough score between the control group and the pre-treatment group(P < 0.05),and there was significant difference in the treatment group(P < 0.01),but there was no significant difference in the night cough score between the control group and the pre-treatment group(P > 0.05),but there was significant difference in the treatment group(P < 0.01).After 3weeks treatment,there were significant differences between the two groups in daytime cough and night cough scores before treatment(P < 0.01),and between the two groups after 3 weeks treatment(P < 0.01).4.Comparison of cough VAS score: at the end of the second week of treatment,there was a significant difference in the cough VAS score between the two groups compared with that before treatment(P < 0 01),and there was significant difference between the two groups after 3 weeks treatment(P < 0 01).There was significant difference between the two groups(P < 0.01).5.Comparison of LCQ score: at the end of the second week of treatment,there was significant difference in the LCQ score between the two groups compared with that before treatment,and there was significant difference between the two groups after 3 weeks treatment(P < 0.0l),and between the two groups 3 weeks after treatment.6.Comparison of TCM syndrome scores: Comparison of the total effective rate: the total effective rate of the control group after treatment was 71.74%,and that of the treatment group was 89.58%.There was significant difference between the two groups(P <0.01).At the end of the second week of treatment,the symptoms of cough in the two groups were significantly different from those before treatment(P < 0.01),and there were significant differences in the symptoms of pharynx itching in the control group(P < 0.05)and in the treatment group(P < 0.01).After 3 weeks of treatment,there were significant differences in cough and pharynx itching between the two groups(P < 0.01).After 3weeks of treatment,there was significant difference in cough symptoms between the two groups(P < 0.05),and significant difference in pharynx itching symptoms between the two groups(P < 0.01).Conclusion: external application of Maiju Fangfeng plaster combined with conventional western medicine is superior to inhaled conventional western medicine in improving FEV1% level of lung function,controlling cough symptoms and improving quality of life in patients with wind-dryness lung cough variant asthma.It is similar to conventional western medicine in reducing airway sensitivity.There are no obvious adverse reactions in the treatment process,and the curative effect is definite,which is suitable for clinical promotion. |
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