| Objectives:1.The purpose of this study is to explore the clinical effect of traditional Chinese medicine in the treatment of bronchiolitis by retrospective analysis,and to provide a better scheme for the treatment of bronchiolitis by comparing the groups2.The purpose of this study is to investigate the effect of traditional Chinese medicine(TCM)in the treatment of bronchiolitis on the asthmatic patients in the future,and to provide basis for clinical prevention of recurrent asthmatic and asthma in children with bronchiolitis.Methods:Collection of medical records of children with bronchiolitis within 2 years of age in the Pediatric Ward of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from January 2015 to December 2018,The basic information(gender,age,birth history,feeding history)and medical history were summarized by electronic course record Before admission,the disease severity,course of disease before admission,TCM single symptom score,past history data(atopic constitution and family history),clinical treatment data(clinical medication situation),disease outcome data(length of stay,disappearance time of symptoms and signs)were recorded in the self-designed case questionnaire.The collected case data were divided into Chinese and Western medicine group and Western medicine group according to whether or not to take traditional Chinese medicine decoction in hospital treatment.The western medicine group was treated with western medicine,and the Chinese and Western medicine group was treated with oral Chinese medicine decoction on the basis of Western medicine treatment according to syndrome differentiation.The clinical efficacy of the two groups was compared and analyzed.The patients were followed up by telephone after discharge.The condition described by parents within one year was determined by the doctor For the diagnosis and treatment data of recurrent wheezing(wheezing recurrence time,cumulative number of wheezing episodes within 1 year after discharge).The data were analyzed by SPSS 24.0 statistical software,and the significance was set as P<0.05.Objective to compare the difference of clinical efficacy between the two treatment methods for bronchiolitis,and analyze the clinical efficacy of Chinese and Western medicine in the treatment of bronchiolitis.Results:In this study,204 cases of bronchiolitis within 2 years old were selected from the study.Including 112 cases in the Chinese and Western medicine group(72males and 40 females),Among them,70 cases were treated with Xiaoqinglong decoction,30 cases were treated with Maxing Shigan decoction,12 cases were treated with Wuhu Decoction and tinglidazao xiefei decoction;And 92 cases in the Western medicine group(64 males and 28 females),There were no differences in gender,age,birth history,feeding history,atopy constitution and family medical history(history of allergic diseases such as asthma and allergic rhinitis among relatives of Grade I or II)in the pre~treatment demographic data Statistical significance(P >0.05),can be comparable;Before admission,the degree of illness,including symptoms,signs,chest radiographs,course of disease,and TCM symptom scores,the difference between the two groups was not statistically significant(P >0.05),and was comparable.In terms of hospitalization time,the course of treatment in the Chinese and Western medicine group was 1 day shorter than that in the Western medicine group,and it had significant statistical significance(P <0.05).The time for the first recurrence of wheezing symptoms in the Chinese and Western medicine group and the Western medicine group was concentrated in the first 3months of follow~up,Among them,48%(54/112)of children in the Chinese and Western medicine group had wheezing recurrence,and 76%(70/92)of the children in the Western medicine group had wheezing recurrence.According to the statistical test,there was a statistically significant difference between the two groups of children in the first 3 months of wheezing recurrence(P <0.001),and there was no statistical difference in the number of children with wheezing recurrence after 3 months of follow~up(P>0.05).There was a statistically significant difference between the two groups of children in the days of normal body temperature,the disappearance time of lung rales,and the disappearance time of wheezing(P<0.05).There was no statistical difference(P>0.05).The Chinese and Western medicine groups are significantly less than the Western medicine groups in terms of the proportion of various medications and the total number of medications.Within 3months after discharge from the hospital,there was a statistically significant difference in the number of cases of wheezing between the two groups(P<0.001),There were statistical differences in the number of cases of wheezing episodes 3times or more(P<0.001);Within 6 months after discharge,The number of cases without wheezing and the number of cases with wheezing 3 or more times were statistically different(P<0.001);After 1 year of follow~up period,The number of cases without wheezing(P<0.001),1 to 2 wheezing attacks(P<0.005),and the number of cases with 3 or more attacks(P<0.001)were statistically different between the two groups.3.Safety evaluation:No adverse reactions and adverse events occurred in the Chinese and Western medicine group and the Western medicine group.Conclusions:After summarizing the data of hospitalized children in the past three years,the results showed that the clinical efficacy of Western medicine combined with oral Chinese medicine decoction in the treatment of bronchiolitis is better than that of Western medicine alone,which can relatively prolong the time of wheezing recurrence after discharge and reduce the number of wheezing attacks. |