The Clinical Study On The Treatment Of Primary Dysmenorrhea With Cold-Stagnation And Blood-Stasis Type By Moxibustion Combined With Acupoint Application

Objective:Through the clinical investigation of Primary dysmenorrheal(PD),this study aims to understand the age distribution of patients,the most common degree of abdominal pain,syndrome classification and the Chinese medicine treatment methods that are easy to be accepted by patients.Patients above the age of 17 and under the age of 35 with cold coagulation and blood stasis of PD with Visual analogue scale(VAS)score of 4-6 were included in the study.Through the clinical observation of moxibustion combined with acupoint application,scientifically evaluate the clinical efficacy of acupoint application and provide a safe and effective method for clinical treatment of PD.Methods:Phase I clinical investigation: collected the data of 203 patients who visited the gynecological outpatient department of the affiliated Hospital of Tianjin Institute of Traditional Chinese Medicine from January 2018 to August 2019 and voluntarily participated in the multicenter PD epidemiological investigation initiated by the gynecological branch of the Chinese society of traditional Chinese medicine.The data in the data system were studied in the first stage to analyze the age distribution of PD patients,the most common degree of abdominal pain,syndrome classification and the Chinese medicine treatment methods that are easy to be accepted by patients.Phase II clinical observation: in September 2019,in January 2020,to participate in the society of Chinese medicine branch of department of gynaecology multicenter PD epidemiological investigation,in the second stage test inclusion criteria and exclusion criteria and volunteered for the moxibustion combined with acupoint sticking therapy haemorrheological nature and blood stasis type PD clinical curative effect observation of 60 patients with clinical studies.The study was carried out in a rigorous experimental manner(randomized double-blind).Both the treatment group(moxibustion combined with dysmenorrhea paste)and the control group(moxibustion combined with comfort paste)were treated for 3 months.Respectively taking records of VAS score,CMSS(COX Menstrual Symptom Scale)score,abdominal pain CMSS score,abdominal pain time,TCM syndrome score according to before and post treatment status which after menstuation.Results:Phase I results: from January 2018 to August 2019,among the 203 PD patients admitted to the affiliated hospital of tianjin institute of traditional Chinese medicine in the department of gynecology,the age of admission was between notoginseng and notoginseng(21≤age<35)common between;VAS scores are most common between 4 and 6;The syndrome was characterized by most cases of cold coagulation and blood stasis.90.1% of PD patients had chosen traditional Chinese medicine for treatment,and the external treatment of traditional Chinese medicine was the most selective,which was the same as traditional Chinese medicine decoction.81.6% of PD patients had received moxibustion treatment,and 67.2% had received acupoint application.Phase II results:(1)Comparison of baseline: general data between two groups before treatment(age,menarche age,course of the disease)and indicators(VAS score,CMSS score,abdominal pain CMSS score,abdominal pain time and TCM syndrome score)the comparison of no statistical significance(P>0.05).(2)Comparison of effective rate: after treatment,the experimental group and the control group were statistically significant in comparison of clinical effective rate and TCM syndrome effective rate(P<0.05).(3)Comparison of observation indicators between the two groups: after treatment,the comparison of observation indicators(VAS score,CMSS score,abdominal pain CMSS score,abdominal pain time,TCM syndrome score)between the experimental group and the control group was highly statistically significant(P<0.01).(4)Comparison of observation indicators in the two groups: the comparison of observation indicators(VAS score,CMSS score,abdominal pain CMSS score,abdominal pain time,TCM syndrome score)in the experimental group and the control group before and after treatment was highly statistically significant(P<0.01).(5)The test process,no medical accidents,no loss of the experimenter,the total loss rate of 0%.Conclusion:Acupoint application can reduce the time of abdominal pain in patients with cold coagulation and blood stasis type PD,reduce the degree of abdominal pain,accompanying symptoms and TCM syndromes,and effectively improve the clinical symptoms of patients with cold coagulation and blood stasis type PD.Moreover,it is safe and effective,with good compliance,and clinical application is recommended.