| Objective to explore the clinical efficacy of xiebai huatan decoction in the treatment of acute exacerbation of chronic obstructive pulmonary disease with phlegm syndrome,and compare it with western medicine alone.Methods subjects,aged 40 to 75 years old between phlegm heat yu lung syndrome of chronic obstructive pulmonary disease in patients with acute aggravating period of 60 cases,by random allocation principles will be allocated into control group and observation group of 30 cases each.The control group was treated with western medicine only,and the observation group combined with Chinese medicine decoction xiebai huatan decoction on the basis of western medicine treatment for 14 days.The improvement of TCM symptom score,c-reactive protein,calcitonin and FEV1%pred before and after treatment were observed.Results1.Clinical syndrome efficacy:overall efficacy of TCM syndromes,and the difference between the observation group and the control group after treatment was statistically significant(P<0.05).2.The amount of cough,phlegm,phlegm,sputum color symptoms integral:after treatment,the observation group and control group in patients with cough,phlegm,phlegm,sputum color symptoms integral,respectively,compared with before treatment,all have improved significantly,the difference statistically significant(P<0.05),superior to that in the control group and observation group improve,statistically significant difference(P<0.05).3.Breathing,chest tightness symptoms integral:after treatment,the observation group and control group patients’ breathing,chest tightness,respectively,compared with before treatment,symptom integral were improved significantly,the difference statistically significant(P<0.05).After treatment,the score of symptoms of wheezing and chest tightness in the observation group showed no significant improvement compared with the control group,and the difference was not statistically significant(P>0.05).4 Serum CRP:after treatment,serum CRP of the observation group and the control group were significantly improved compared with those before treatment,and the difference was statistically significant(P<0.05).After treatment,serum CRP were significantly improved in the observation group compared with the control group,and the difference was statistically significant(P<0.05).5.Lung function:the observation group and control group after treatment the lung function FEV1%Mr Pred,respectively,compared with before treatment,all have improved significantly,the difference statistically significant(P<0.05),the observation group after treatment compared with the contrast between the way Mr Pred lung function FEV1%difference has no statistical significance(P>0.05).Conclusion Through this experiment,it can be seen that the addition and reduction of the decoction of the decoction to the acute exacerbation of chronic obstructive pulmonary disease of phlegm.There is a better therapeutic effect in the heavy period,which is better than the clinical efficacy of western medicine in some data. |