| Objective:At present,for patients with mild-moderately severe gallstone acute pancreatitis,there is no consensus on the appropriate timing of cholecystectomy.To explore the clinical effects of laparoscopic cholecystectomy at different timings in the treatment of mild to moderate severe biliary acute pancreatitis,and to provide a reference for the clinic al selection of appropriate surgical timing.Clinical data and Methods:This study retrospectively analyzed the clinical data of 227 patients with mild to moderate severe biliary acute pancreatitis treated with cholecystectomy.Divided into 3 groups according to the timing of surgery,early cholecystectomy: group 1(≤ 3 days);delayed cholecystectomy:group 2(≤7 days)and group 3(>7 days).Statistical comparisons were made on the time to symptom relief,recurrence of pancreatitis,surgical safety,incidence of complications,total length of stay,and total hospital costs in different treatment groups.Results:There were no significant differences in the operation time,intraoperative blood loss,conversion rate to laparotomy,postoperative complication rate,pancreatitis recurrence rate,re-admission rate of pancreatitis recurrence after discharge,and secondary surgical intervention in the three groups.The incidence of operative field adhesions,total length of hospital stay and total medical consumption in the early surgery group were lower than those in the delayed surgery group,and the difference was statistically significant.Conclusion:In patients with mild-moderately severe gallstone acute pancreatitis,it is safe and feasible to perform laparoscopic cholecystectomy at an early stage(≤3 days)after a clear diagnosis,and will not increase the difficulty of the operation and the incidence of perioperative complications.And it can reduce the patient’s risk of recurrence of pancreatitis during the waiting period,and can reduce the length of hospitalization and reduce the total hospitalization cost. |
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