| Objective:Aimed to explore the effect of preoperative oral low-concentration carbohydrate on quality of recovery in patients undergoing thyroidectomy.Methods:120 patients,aged 18～65 years,AS A physical status Ⅰ～Ⅱ,scheduled for elective open thyroidectomy,were equally and randomly divided into three groups by random number table:oral intake of 300 mlcarbohydrate solution(CH group)or300ml pure water(PW group)2h before surgery and fasting for 8h before surgery(F group).All patients adopt the same treatment measures except for the intervention,and received total intravenous anesthesia(TIVA)with endotracheal intubation.Following indexes were recorded:Quality of Recovery-15 Score(QoR-15)at 1day before surgery(T0),24h,48h,72h after surgery(T1,T2,T3);perioperative blood glucose;perioperative patient discomfort;numerical rating scale(NRS)at rest(NRS-R)and during a deglutition or with movement(dynamic,NRS-D);preoperative gastric volume;intraoperative vital signs;postoperative nausea or vomiting;time to gastrointestinal recovery;length of postoperative stay and so on.Results:The QoR-15 scores in the CH and PW groupwere statistically higher than the F group at T1(P<0.05),but theenhancement of recovery quality reached the clinical significancein the only CH group(Minimal clinically important difference,MCID≥8).For the five dimensions of the QoR-15 questionnaire:physiological support,physical comfort and emotional dimension in the CH group were significantly better than the F group(P<0.05)at T1.Besides,blood glucose in the CH group was significantly lower than the PW group and F group at each time point after surgery.Conclusion:Preoperative orallow-concentration(4.8%)carbohydrate can improve the patient-centred quality of recovery on patients undergoing thyroidectomyat theearly stage postoperatively,and stabilize the perioperative blood glucose. |
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