Analysis Of The Incidence And Risk Factors Of Postoperative Nausea And Vomiting In Patients Undergoing Video-assisted Thoracic Lung Resection

Objective:To observe the incidence of postoperative nausea and vomiting(PONV)in patients undergoing video-assisted thoracic lung resection,and analyze its risk factors.Methods:A total of 436 patients who underwent elective video-assisted thoracic lung resection and complete case data at the Fourth Hospital of Hebei Medical University from January 1,2019 to December 31,2019 were included in this study.The relevant clinical data of the patients were collected and patients were divided into P group and N group according to whether nausea and vomiting occurred in 48 h after surgery.Patients in group P developed nausea and vomiting after surgery,while patients in group N did not develop nausea and vomiting after surgery.Respectively for gender,age,body mass index,ASA classification,basic diseases,previous surgical history,smoking history,drinking history,history of motion sickness,Nerve block method,intraoperative fluid replenishment,anesthesia time,operation time,and operation method were analyzed by univariate Logistic regression analysis.Multivariate Logistic regression analysis was used to analyze the single factors affecting PONV of patients,and P<0.05 was considered as statistically significant.Results:A total of 436 patients were enrolled in this retrospective study,of which 106 patients were excluded,and finally 330 patients were included in this study.109 patients had PONV,with an incidence rate of 33.0%.Single factor logistic regression analysis shows that gender,body mass index,cardiovascular system disease,smoking history,drinking history,history of motion sickness,total fluid volume were related to the occurrence of PONV(P<0.05).Multivariate Logistic regression analysis revealed two independent risk factors for PONV: female(OR 5.060;95%CI 2.913～8.791;P<0.001);lower body mass index(OR 0.891;95%CI 0.826～0.961;P=0.003).Conclusions:PONV occurred in 33.0% of patients after video-assisted thoracic lung resection.Female and lower body mass index are independent risk factors for PONV.