A Study Of The Application Of Bispectral Index In Patients With Mechanical Ventilation

Objectives To investigate whether the bispectral index(BIS)can be used as a useful tool for monitoring the depth of sedation in patients with invasive mechanical ventilation in the intensive care unit(ICU).We also compared the difference between the application of BIS to monitor the depth of sedation and the use of Richmond agitation-sedation scale(RASS)to provide clinicians with a more accurate and objective means of monitoring the depth of sedation.Methods 59 patients admitted to the ICU of Hebei Provincial People’s Hospital for tracheal intubation and requiring sedation from September 2020 to December 2020 were prospectively analyzed.The included patients were divided into a BIS monitoring group(test group)and a RASS monitoring group(control group)by a coin toss method.The depth of sedation was maintained at shallow sedation in both groups.The BIS score of the test group was maintained at 60-80,and the BIS value was used as the basis for regulating the dosage of sedative drugs;the RASS score of the control group was maintained at-2-0,and the dosage of sedative drugs for the patients was regulated according to the RASS score.Relevant clinical information and data were collected and recorded for both groups.Subsequently,clinical analysis was performed using SPSS13.0.Results A total of 59 patients were finally included in the study,29 in the test group and30 in the control group.The differences between the two groups in terms of gender,age,severity of illness(expressed as acute physiology and chronic health evaluation scoring system Ⅱ),and disease involvement system were not statistically The two groups were comparable.There were no statistically significant differences between the test and control groups in the incidence of adverse effects(including hypotension,too deep or too shallow sedation,bradycardia,etc.)and the number of ICU days(2.55±0.572 vs.2.63±0.556,p>0.05);and in the rate of combined application of other sedative drugs(17.24% vs.17.2%vs.43.3%,p<0.05),total use of propofol(2327.59±504.90 vs.2616.67±536.324,p<0.05),and hours of ventilator use(42.38±5.41 vs.45.90±7.58,p<0.05),the differences were statistically significant.Conclusions The BIS monitor allows continuous monitoring of the patient’s depth of sedation at the ICU bedside.Compared to the RASS score,BIS-monitored sedation can reduce the use of sedative drugs,shorten the patient’s mechanical ventilation time,and reduce the rate of co-medication.Figure [4];Table [7];Reference [162]...