Accelerated Weight-bearing Rehabilitation Protocol Following Anterior Cruciate Ligament Reconstruction:a Systematic Review And Meta-analysis

Objective:To compare accelerated and delayed weight-bearing rehabilitation of anterior cruciate ligament reconstruction（ACLR）regarding clinical outcome measures of knee function（International Knee Documentation Committee Subjective Knee Form（IKDC）,Lysholm Knee Scoring Scale,Tegner Activity Scale,and Knee Injury and Osteoarthritis Outcome Score（KOOS））,knee laxity,range of movement（ROM）,quadriceps,and bone tunnel enlargement.Methods:Systematic searches of Embase,MEDLINE,CINAHL,and the Cochrane Library databases for studies comparing delayed or accelerated weight-bearing rehabilitation protocol after ACLR in adult patients,from inception to February 2021,were performed.Results:Nine studies met the eligibility criteria.A meta-analysis revealed a higher risk of knee laxity in the accelerated weight-bearing group.Accelerated weight-bearing may be related to higher IKDC scores,while there was no statistical difference for Lysholm,Tegner,and KOOS scores at a follow-up within two years.Four of five studies reported no statistical difference for quadriceps strength and ROM scores,while two studies reported bone tunnel enlargement in the accelerated weight-bearing group.Conclusions:This systematic review confirmed that accelerated weight-bearing caused more serious knee laxity and bone tunnel widening than delayed weight-bearing after ACLR.We,therefore,recommend clinicians should select postoperative rehabilitation programs cautiously.