Clinical Study On The Treatment Of Stable Angina Pectoris Of Coronary Heart Disease (Qi Stagnation And Blood Stasis Syndrome) With Anti Angina Prescription

ObjectiveTo observe and evaluate the efficacy and safety of anti angina prescription in the treatment of coronary heart disease stable angina(qi stagnation and blood stasis syndrome).Methods1.In this study,a randomized,controlled clinical research method was used.The subjects were selected from the inpatients and outpatients of huayuanshan District of Hubei Provincial Hospital of traditional Chinese medicine from January 1,2019 to December 31,2020 in the Department of cardiovascular medicine.62 patients with stable angina pectoris of coronary heart disease(qi stagnation and blood stasis syndrome)were selected according to the inclusion criteria.Methods: 62 patients were randomly divided into experimental group(31 cases)and control group(31 cases).The total course of treatment was 4 weeks.2.Observe the angina pectoris index(attack frequency,pain degree,duration)and integral,TCM syndrome and integral,ECG changes,nitroglycerin dosage and stopping rate of the two groups before and after treatment,so as to evaluate the effectiveness of anti angina pectoris prescription in the treatment of stable angina pectoris(qi stagnation and blood stasis syndrome)of coronary heart disease.3.To evaluate the safety of self-made prescription by observing and comparing the general situation,vital signs,blood,urine,feces,liver and kidney function of the subjects before and after treatment.4.All data were analyzed by spssau software.Results1.There was no significant difference in age,gender,angina pectoris index,combined with basic diseases between the two groups before treatment(P > 0.05),which was comparable.2.Curative effect of angina pectoris: the effective rate of the experimental group was 83.87%,and that of the control group was 35.48%.After comparison,the curative effect of the experimental group was better than that of the control group,and the difference was statistically significant(P < 0.05).3.Change of angina pectoris score: before treatment,there was no significant difference in angina pectoris score between the experimental group and the control group(P > 0.05),which was comparable.After treatment,the scores of angina pectoris in the two groups were lower than before treatment,and the difference was statistically significant(P < 0.05),but the scores of angina pectoris in the experimental group were lower than those in the control group,and the difference was statistically significant(P < 0.05).4.TCM syndrome curative effect: the effective rate of the experimental group was 87.10%,and that of the control group was 45.16%.After comparison,the curative effect of the experimental group was better than that of the control group,and the difference was statistically significant(P < 0.05).5.TCM syndrome integral change: before treatment,there was no significant difference in TCM syndrome integral between the experimental group and the control group(P > 0.05),which was comparable.After treatment,the TCM syndrome scores of the two groups were lower than before treatment,the difference was statistically significant(P < 0.05),but the TCM syndrome scores of the experimental group were lower than those of the control group,and the difference was statistically significant(P < 0.05).6.ECG efficacy: after comparison,the effective rate of the experimental group was 77.41%,and that of the control group was 16.13%.The difference between the two groups was statistically significant(P < 0.05).7.Safety: after comparison,there was no obvious abnormality in vital signs,blood,urine and feces,blood lipid,blood glucose,liver and kidney function and blood viscosity of the two groups before and after treatment.ConclusionIt is safe and effective to treat stable angina pectoris of coronary heart disease(qi stagnation and blood stasis syndrome)with self-made anti angina prescription.