Study On The Distribution Of Eye Biological Parameters Of Adolescent-children Aged 3-18 And Their Relationship With Refractive Status And Physical Development

Objective:Explore the distribution of biological parameters of the eyes of adolescents and children,and explore its relationship with age,gender,refractive status and other parameters,and further explore the role of physical development in the development of myopia.Methods:Our research is a cross-sectional research.We randomly selected 304 cases(608 eyes)of adolescents and children aged 3-18 years who underwent refractive examinations at the Department of Ophthalmology,Affiliated Hospital of North Sichuan Medical College from March 2020 to October 2020,and passed the cycloplegia refraction and optical biometer.(IOLMaster 700)Obtain equivalent spherical power(SE),axial length(AL),corneal refractive power(horizontal corneal refractive power K1 and vertical corneal refractive power K2,calculate the average corneal refractive power Km),anterior chamber depth(ACD),lens Thickness(LT),and calculate the corneal radius of curvature(CR),the ratio of the axial corneal curvature radius(AL/CR,abbreviated as axial ratio),the thickness of the vitreous cavity(VCD),measure and record the height and weight according to the standard plan,and calculate the body mass index(BMI),According to the equivalent spherical degree,the test group was divided into 2 groups,namely the myopia group(SE≤-0.50D)and the non-myopia group(SE>-0.50D).And according to different ages:3-6 years old preschool group,7-12 years old school age group,13-18 years old teenagers group.Statistical analysis was performed using SPSS 22.1.Analyze the distribution of ocular biological parameters and calculate the correlation between equivalent spherical power and ocular biological parameters,and explore the correlation between age,gender,height,weight,eye axis,and equivalent spherical power.Results:In this study,the overall prevalence of myopia in the 304 adolescents and children aged 3-18 years(608 eyes)was 63.16%,among which the prevalence of myopia was 3-6 years old,7-12 years old,and 13-18 years old.They were 13.56%,72.44%,and 88.75%in turn.The myopia rate showed an upward trend with age.There was a statistically significant difference in the prevalence of myopia between different age groups(P<0.05).The prevalence of myopia in men and women was statistically significant(P<0.05).The difference was not statistically significant(P>0.05);this study established a linear regression model between the refractive power and the biological parameters of the eye and showed that under the influence of age,gender,and height,the three refractive parameters of VCD,CR,and LT Can explain 65.2%of the total variation of SE.With age,the AL,ACD,VCD,and AL/CR ratios become larger,LT and SE become smaller,while CR and CCT are based on stability;through the establishment of a regression model between physical development and refractive power and refractive parameters,it is found that height,BMI is positively correlated with AL,ACD,AL/CR ratio,CR and VCD,negatively correlated with SE and LT,and weight is positively correlated with SE.Conclusion:With age,the length of the eye axis becomes longer,the depth of the anterior chamber becomes deeper,the AL/CR ratio becomes larger,the length of the vitreous cavity becomes longer,the thickness of the lens becomes thinner,and the refractive state tends to be myopia,while the radius of curvature of the cornea and the thickness of the central cornea There is little change in different age groups.VCD,CR,LT are the main determinants of refractive status in children and adolescents’ refractive development.This study confirmed that there is a certain correlation between the growth and development of children and adolescents and refractive development,and further confirmed that there may be a common developmental channel or pathway between height and eye axis.