| Objective: Through clinical observation,To evaluate the clinical effect of tutor’s experience of Tongfurunchang decoction on functional constipation with heat aggregate and colon dryness.To explore a more effective clinical method to treat functional constipation.Methods: A total of 85 cases with functional constipation due to heat aggregate and colon dryness who visited the outpatient department and inpatient department of anorectal department of hebei hospital of traditional Chinese medicine from January 2018 to November 2019 were selected.The patients were divided into treatment group and control group according to the random number table method.There were 43 cases in the treatment group and42 cases in the control group.The treatment group was given Tongfurunchang decoction,Daily 1 agent,Warm in the morning and evening dress;Control group was given lactulose oral solution orally,15ml/time,2 times/day,take it orally morning and evening after meals.Both groups were treated for 10 days,a total of 6 sessions.The constipation symptom scores and quality of life scores of the two groups were recorded before and after 6 courses of treatment.The recurrence rate and safety were compared.Result: All 85 cases in this study met the inclusion criteria and they were no shedding during the treatment.There was no significant difference in age,sex and course of disease between the two groups(P>0.05),have comparability.After 6 courses of treatment,Major symptom scores before and after treatment、the efficacy of quality of life score、curative effect and recurrence rate after 3 months of follow-up were compared between the two groups.And the safety of the whole treatment process was evaluated.Details are as follows:1.It was found by intra-group comparison: After 6 courses of treatment,the main symptom scores of patients in both groups were lower than before treatment.,and the difference between the two groups was statistically significant(P<0.05);Comparisons between groups were found:There was no significant difference in main symptom scores between the two groups before treatment(P>0.05).After treatment,the treatment group had a more significant reduction in the main symptom score than the control group,and the difference was statistically significant(P<0.05).2.Intra-group comparison was found:After 6 courses of treatment,the scores of PAC-QOL scale were lower in both groups than before treatment,and the difference was statistically significant(P<0.05).Comparisons between groups were found:There was no significant difference in the scores of PAC-QOL scale between the two groups before treatment(P>0.05).After treatment,the reduction of pac-qol scale scores was more significant in the treatment group than in the control group.The difference was statistically significant(P<0.05).3.The effective rate after treatment was 90.69%,among them,10 cases were cured,17 showed obvious effect,12 were effective and 4 were ineffective;The effective rate of the control group was 73.81%,among them,5cases were cured,11 showed obvious effect,15 were effective and 11 were ineffective.The effective rates of the two groups were tested by the rank sum test,the difference was statistically significant(P<0.05).4.The patients were followed up for 3 months after treatment.In the treatment group,there were 8 cases of recurrence,the recurrence rate was20.51%;The control group had 16 cases of recurrence,the recurrence rate was51.61%.Two results were not significant difference by statistics analysis(P<0.05),the recurrence rate of the treatment group was lower than that of the control group.5.The adverse reactions occurred in the two groups of patients during the treatment could be improved without other treatment.Both treatments are safer.Conclusion:The main symptoms of functional constipation with heat aggregate and colon dryness can be effectively improved by Tongfurunchang decoction,improvingquality of life,curative effect lasting,good safety.It is worthy of clinical promotion and application. |
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