Analysis Of Gender Differences In Depression And Anxiety Of Inpatients With Depression In A Third-level Grade-A Hospital In Nanjing From 2016 To 2018

Objectives: The purpose of this study is to investigate whether there are gender differences in depression,anxiety level and clinical manifestations of inpatients with depression and its influencing factors.Through the study,we try to provide some basis for the prediction of depression in primary health care,the diagnosis of depression by clinicians,and the identification of residual symptoms of depression by patients themselves and their families.Methods: Through consulting the medical records of 915 inpatients with depression in a third-level grade-A hospital in Nanjing from 2016 to 2018,the social demographic data and clinical data of inpatients with depression were collected,and Excel data file was established.The final number of research cases was determined according to the inclusion and exclusion criteria.According to the total score of Hamilton Depression Scale,the original data of the included inpatients were divided into four groups: "0-6 points","7-16 points","17-23 points","24 points and above".According to the total score of Hamilton Anxiety Scale,the original data of the included inpatients were divided into five groups: "0-6 points","7-13 points","14-20 points","21-28 points","29 points and above".We conducted univariate and multivariate analysis on the overall depression level and anxiety level of inpatients.The original data of the included inpatients were divided into male group and female group.We analyzed the differences of depression and anxiety symptoms.Data entry was double blind,and SAS 9.4 was used for statistical analysis.The enumeration data was expressed in frequency and rate,and the measurement data was expressed in median(quartile range).Wilcoxon test and Kruskal Wallis H test were used in univariate analysis.Ordered logistic regression was used in multivariate analysis.We used stepwise regression method to screen variables,taked α = 0.05 as the inclusion level and P < 0.05 as the result test level,and calculated the odds ratio and its 95% confidence interval.Spearman rank correlation was used in correlation analysis.Results: According to the inclusion and exclusion criteria,the final number of cases was determined as 773.Among the 773 inpatients in this study,224 were male,accounting for 28.98%;549 were female,accounting for 71.02%;the ratio of male to female was about 1:2.45.Univariate analysis showed that there were statistically significant differences in overall depression level of the inpatients with different marital status and family history of mental illness(P<0.05).Multivariate analysis showed that there were statistically significant differences in overall depression between unmarried inpatients and divorced inpatients,inpatients with or without family history of mental illness(P<0.05).And the overall depression level of unmarried inpatients was lower than that of divorced inpatients(OR=0.43,95%CI=0.19-1.00),the overall depression level of inpatients with family history of mental illness was higher than that of inpatients without family history of mental illness(OR=1.57,95%CI=1.00-2.46).Univariate analysis showed that there were statistically significant differences in overall anxiety level of inpatients with different gender,marital status,age(P<0.05).Multivariate analysis showed that the overall anxiety level of inpatients with different genders was statistically significant(P<0.05).And the overall anxiety level of female inpatients with depression was higher than that of male inpatients with depression(OR=1.42,95%CI=1.06-1.91).The average rank of depression,difficulty in falling asleep,tension,sensory system,cardiovascular system,gastrointestinal tract and autonomic nervous system in female inpatients with depression was higher than that in male inpatients with depression.The average rank of sexual and genitourinary symptoms in male inpatients with depression was higher than that in female inpatients with depression.In terms of factor structure,the average rank of sleep disorder and somatic anxiety in female inpatients with depression was higher than that in male inpatients with depression.There was a positive correlation between the scores of Hamilton Depression Scale and Hamilton Anxiety Scale in all inpatients,male inpatients and female inpatients(P<0.0001),and the degree of correlation is relatively high.Conclusion: Among the inpatients with depression,those with poor marriage quality or family history of mental illness had more severe depression.Female inpatients with depression were more anxious than male inpatients with depression.Female inpatients with depression were more serious than male inpatients with depression in depression,difficulty in falling asleep,tension,sensory system,cardiovascular system symptoms,gastrointestinal tract and autonomic nervous system.Male inpatients with depression are more serious than female inpatients with depression in sexual and genitourinary symptoms.Sleep disorder and somatic anxiety in female inpatients with depression are more serious than that in male inpatients with depression.There is a strong positive correlation between depression and anxiety.