Clinical Observation Of Buyang Huanwu Decoction Combined With EECP On Patients With Qi Deficiency And Blood Stasis Type Of Stable Angina Pectoris

Objective:To observe the effect of Buyang Huanwu Decoction combined with enhanced external counterpulsaption(EECP)on angina pectoris,TCM score,high-sensitivity C-reactive protein(hs-CRP),cardio-ankle vascular index(CAVI),blood lipid(TC,TG,LDL-C,HDL-C)and other arteriosclerosis related indicators in patients with Stable angina pectoris(SAP)of qi deficiency and blood stasis syndrome,to explore the clinical efficacy of Buyang Huanwu Decoction combined with EECP on SAP of qi deficiency and blood stasis type,to provide a SAPfe and effective treatment for patients,and in clinical promotion.Methods:A total of 120 SAP patients with qi deficiency and blood stasis syndrome were randomly divided into control group(n = 40)and combined group(n = 40).The control group was treated with conventional western medicine;the control group was treated with basic Buyang Huanwu Decoction;combined with the basic EECP treatment of the traditional Chinese medicine group,the course of treatment was 35 days.The degree of angina pectoris,TCM score,hs-CRP,CAVI,blood lipid and other indicators were observed before and after treatment in the three groups,and the results were statistically analyzed.Result:1.112 cases were actually completed,including 39 cases in the control group,37 cases in the traditional Chinese medicine group and 36 cases in the combined group.There was no significant difference in the general data(gender,age,course of disease,past history,etc.),CCS grade,degree of angina pectoris,TCM score,hs-CRP,CAVI and blood lipid level among the three groups before treatment(P > 0.05),with comparability.2.In the improvement of angina pectoris: the total effective rate of the TCM group(67.57%)was better than that of the control group(48.72%),and the total effective rate of the combined group(83.33%)was better than that of the TCM group(P < 0.05).3.In terms of the curative effect of TCM: after treatment,the TCM scores of the three groups were significantly lower than those before treatment(P < 0.01);compared with the control group,the overall response rate of the TCM group(78.38%)was better than that of the control group(51.28%),and the overall response rate of the combined group(94.44%)was better than that of the TCM group,P < 0.05.4.In terms of the improvement of hs-CRP indicators: there was no statistical difference in the control group before and after treatment(P > 0.05),and the hs-CRP level in the combined group after treatment was significantly lower than that before treatment(P< 0.01);the decrease in the combined group was significantly better than that in the traditional Chinese medicine group(P < 0.05).5.In terms of the improvement of CAVI indicators: after treatment,the CAVI levels of the three groups were significantly lower than those before treatment(P < 0.01);compared,the traditional Chinese medicine group was superior to the control group(P < 0.05),and the combined group was superior to the traditional Chinese medicine group(P < 0.05).6.Improvement of blood lipid level: After treatment,TC,TG and LDL-C levels in the three groups were significantly lower than those before treatment(P < 0.01).Compared with the control group,the decrease in the traditional Chinese medicine group was better(P< 0.05),and there was no statistical difference in the combined traditional Chinese medicine group(P > 0.05);there was no statistical difference in HDL-C level compared with that before treatment(P > 0.05).7.Monitoring of SAPfety indicators: There was no statistical difference in the SAPfety indicators of the three groups before and after treatment(P > 0.05),and no adverse reactions occurred in the subjects.Conclusion:1.On the basis of conventional western medicine treatment,Buyang Huanwu Decoction can better improve the clinical symptoms,TCM,hs-CRP,CAVI,blood lipid(TC,TG,LDL-C)related indicators of SAP patients with qi deficiency and blood stasis type,suggesting that Buyang Huanwu Decoction can reduce the level of inflammatory factors,regulate metabolism,reduce arterial stiffness,and play a role in anti-arteriosclerosis.2.Buyang Huanwu Decoction combined with EECP treatment can further improve the clinical symptoms,TCM,hs-CRP and CAVI levels of SAP patients.