| Objective:Based on the method of Yi Qi Sheng Yang,Tongqiao umbilical paste combined with Xie’s Wenbi Tongqiao Decoction was used to treat allergic rhinitis of spleen and lung deficiency and cold,and its clinical efficacy was observed.At the same time,it is explored whether Tongqiao umbilical paste can maintain the clinical efficacy of allergic rhinitis,achieve the purpose of clinical control,and improve the patient’s Minimal persistent inflammationin,and improve its long-term efficacy.And then to evaluate its safety and effectiveness,hoping to provide new treatment ideas and new adjuvant treatment techniques for improving the long-term efficacy of allergic rhinitis.Methods:According to the RAND function grouping,60 patients were randomly divided into two groups,30 in the treatment group and 30 in the control group.The general information and biological distribution of all subjects were not statistically different and comparable.In the first stage,patients in the treatment group were treated with Xie’s Wenbi Tongqiao Decoction combined with Tongqiao umbilical paste,and patients in the control group were treated with Xie’s Wenbi Tongqiao Decoction combined with placebo umbilical paste.In the second stage,the treatment group was treated with Tongqiao umbilical patch and the control group Use placebo umbilical patch to continue treatment;one dose of traditional Chinese medicine particles a day,umbilical patch once every 2 days,and stick to Shenque point,usually 4-6 hours.60 days is a course of treatment,divided into two stages,each stage is 30 days.At the end of each stage,observe the score changes of the symptoms,signs and TCM symptoms of the two groups of subjects before and after treatment.All collected data are processed and analyzed by the computer SPSS 23.0 statistical software.Outcome:1.After the end of the first stage of treatment,the two groups(excluding falling cases,28 total cases in the treatment group,29 total cases in the control group)of symptoms,signs,and TCM syndrome scores were compared with those before treatment,and the scores were compared within the group.Compared with the previous level,P<0.05;the total clinical effective rate of the treatment group was 92.85%,and the overall efficacy interval distribution was significantly Significantly effective: effective: ineffective:13:13:2;the control group clinical total effective rate was 82.75%,and the overall efficacy interval distribution was higher significantly Significantly effective: effective:ineffective: 9:15:5.the comparison between the two curative effect groups P>0.05,the difference is not statistically significant,which proves that the two treatment programs have achieved significant clinical curative effects;in the overall curative effect interval distribution,the treatment group The interval distribution of markedly effective cases is better than that of the control group,and the interval distribution of ineffective cases is smaller than that of the control group,suggesting that the overall effect interval distribution of the treatment group is better than that of the control group.2.After the first stage of treatment,the total scores of symptoms,signs and the total of TCM syndromes of the two sets after the first section of treatment were compared with the scores of various symptoms,signs and TCM syndromes.P>0.05,indicating After the completion of the first stage of treatment,the symptoms,signs and TCM syndrome scores of the two groups of patients were similar.3.After the second stage of treatment,the total effective rate of the treatment group was 96.43% higher than before by 3.58%,and the total effective rate of the control group was 79.31% lower than before by 3.44%.And In terms of the overall curative effect interval distribution,the treatment group is more effective: effective: invalid is 15:12:1;the control group is more effective:effective: invalid is 11:12:6,and the overall curative effect interval.Comparing the two groups’ efficacy,P<0.05,the efficacy was statistically different and distribution of the treatment group is still better than that of the control group.In addition,the symptoms,signs,and TCM syndrome scores of the two groups were compared with those at the completion of the first stage treatment.In the treatment group,nasal congestion,runny nose,sneezing,spontaneous sweating,loose stools,fatigue and symptoms of nasal body The scores were significantly lower than before,and the scores for nasal itching and aversion to cold were comparable to those at the completion of the first stage treatment.The scores of the control group were similar to those at the completion of the first stage treatment,suggesting that the Tongqiao umbilical paste in the treatment group can maintain and improve the clinical efficacy of the first stage.Tongqiao umbilical paste can improve nasal congestion,runny nose,sneezing,spontaneous sweating,loose stools,symptoms of fatigue and nasal signs in allergic patients with spleen and lung deficiency-cold type;Wenbi Tongqiao drink has a definite clinical effect,and the clinical effect can at least be maintained 1 month.4.After the second stage of treatment,the total scores of symptoms and signs and the total scores of TCM syndromes of the two groups of patients after the second stage of treatment were compared between groups,P<0.05,and the total scores of the two groups of patients after the second stage of treatment were compared.Comparing the symptoms,signs and TCM syndrome scores between groups,nasal congestion,runny nose,fatigue,P<0.05,nasal itching,sneezing,nasal signs,aversion to cold,spontaneous sweating,loose stools,P>0.05,suggesting that the umbilical cord The patch can improve the symptoms of nasal congestion,runny nose,and fatigue in patients with allergic spleen and lung deficiency and cold type.5.During the treatment,there were no adverse reactions in the two groups,and the safety evaluation of Tongqiao umbilical paste was level 1.6.3-month follow-up of curative effect,24 patients in the treatment group were evaluated for 3-month curative effect,the total effective rate was 83.33%,and the distribution of curative effect was markedly effective: effective: invalid was 9:11:4.22 patients in the the control group were evaluated for 6-month curative effect,the total effective rate is 59.09%,and the distribution of curative effects is markedly effective: effective: invalid is 6:7:9.The statistical analysis result P<0.01,which is statistically significant,indicating that Tongqiao umbilical paste can improve allergic rhinitis of spleen and lung deficiency and cold The long-term effect.Conclusion:This study is based on the method of replenishing qi and promoting yang.The study found that Xie’s Wenbi Wenbi Tongqiao Decoction combined with Tongqiao umbilical paste has a positive clinical effect in the treatment of allergic rhinitis of spleen and lung deficiency and cold.The use of Tongqiao umbilical paste for 2 months can improve the patient’s Minimal persistent inflammation,effectively maintain and improve the clinical efficacy of allergic rhinitis of spleen and lung deficiency and cold type,further improve symptoms,signs and TCM syndromes,achieve clinical control and increase allergies The long-term curative effect of rhinitis can improve the quality of life of patients with rhinitis,and the Tongqiao umbilical patch is easy to use,safe and low in cost. |
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