| ObjectiveThis study aims to Leicester Cough Questionnaire(LCQ)score,cough symptoms integral,a comprehensive evaluation of TCM symptom score,etc so as to explore and subtract the clinical curative effect of modified Sangbaipi decoction in treating post infectious cough with phlegm-heat stagnating in lung.MethodsA prospective randomized controlled trial was conducted in this study,60 patients who were admitted to the department of respiratory department of guangzhou traditional Chinese medicine hospital were selected to meet the criteria for the inclusion of post infectious cough with phlegm-heat stagnating in lung,and the patients were randomly divided into treatment group and control group of 30 patients.The treatment group was given the treatment of Compound methoxynamine capsules and modified Sangbaipi decoction,the control group was given the treatment of Compound methoxamine capsules,and the treatment course of both groups was 7 days.Observed two groups of patients before and after treatment of Leicester Cough Questionnaire score,cough symptom integral and the TCM symptom score,at last,through analysis of relevant data and specific conclusions.Results1.Comparison of LCQ score: Compared with the previous treatment group,the LCQ physiological region score,psychological region score,social region score and total score of the treatment group were higher than before(P<0.05).LCQ social region score after treatment in the control group was no different from that before treatment(P>0.05),and LCQ physiological region score,psychological region score and total score were all higher than before(P<0.05),indicating that both treatment regimens could improve the quality of life of patients as a whole.After treatment,compared with the control group,the treatment group was more effective in improving the quality of life of patients(P<0.05).2.Comparison of cough symptom score:Compared with group before treatment,the treatment group patients after treatment of daytime cough symptoms integral,cough cough symptoms integral,night symptom scores were compared with the previous reduced(P <0.05);Control group after treatment in patients with daytime cough symptoms integral,cough cough symptoms integral,night symptom scores were compared with the previous reduced(P<0.05),two groups of treatment can be effective relief to cough sufferers.However,compared with the control group after treatment,the treatment group in alleviating cough symptoms in patients with better effect(P <0.05).3.Comparison of TCM syndrome score and clinical efficacy: Compared with group before treatment,the treatment group after treatment in patients with TCM symptom score were reduced(P<0.05),earlier in the control group after treatment in patients with TCM symptom scores were compared with the previous reduced(P<0.05),two groups of treatment are to a certain extent in patients with cough,cough up phlegm,shortness of breath and dry mouth.However,compared with the control group,the treatment group had better efficacy in alleviating the overall clinical symptoms of the patients(P <0.05).The treatment group was effective in 29 cases and 1 case was invalid.In the control group,25 cases were effective and 5 were invalid.The total effective rate of the treatment group was 96.67%,the total effective rate of the control group was 83.33%,the total effective rate of the treatment group was higher than that of the control group,and the clinical efficacy of the treatment group was better than that of the control group(P<0.05).4.During the treatment,no adverse reactions were observed in both groups,and it was proved safe and effective for the treatment of post infectious cough with phlegm-heat stagnating in lung with modified Sangbaipi decoction.ConclusionModified Sangbaipi decoction with Compound methoxamine capsules treatment post infectious cough with phlegm-heat stagnating in lung,can effectively improve the patient’s clinical symptoms and quality of life,curative effect is superior to the simple application of Compound methoxamine capsules. |
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