A Study On The Law Of Medicine Used By Traditional Chinese Medicine Master In The Treatment Of Stomach Stuffiness

ObjectiveBased on the medical cases of the treatment of stomach stuffiness by the master of Chinese medicine,the data mining is carried out by using the modern statistics and computer mathematical analysis method to explore the characteristics of syndrome differentiation and treatment and the law of medicine,extract the main syndrome types and corresponding core drug groups and core drug combinations,analyze the characteristics of the etiology and pathogenesis of the present and contemporary stomach stuffiness,inherit the treatment experience of the traditional Chinese medicine master,and further develop step to clarify the advantages of modern and contemporary Chinese medicine in the treatment of stomach stuffiness,so as to guide the clinical work and future research direction.MethodReferring to the relevant diagnostic standards of stomach stuffiness,taking "stomach stuffiness" and the name of the Traditional Chinese Medicine Master as key words,the relevant doctor’s documents are searched in the large-scale medical literature collection database,the clinical manifestations and prescriptions of the medical cases of the treatment of stomach stuffiness by the traditional Chinese medicine masters are extracted and processed in a unified and standardized way,and the medical case information that meets the standards is entered to establish the database and transport it with the statistical methods of frequency analysis,factor analysis,cluster analysis,correlation analysis and Logistic regression analysis,combined with the analysis function of the cloud platform of ancient and modern medical cases,this paper summarizes the symptoms of the treatment of stomach stuffiness by the traditional Chinese medicine masters and the characteristics of drug selection.Result1.There are 219 medical cases about the treatment of stomach stuffiness,involving 36 doctors and 146 literatures.2.General information of medical cases:(1)gender: there are 216 records of patients’ gender information,including 103 males and 113 females.(2)age: the minimum age of the patients was 15 years,the maximum age was 81 years,and the incidence rate of age group35 to 64 was significantly higher than that of other age groups.3.Medical case diagnosis and syndrome differentiation:(1)the frequency of Western medicine diagnosis was 182 times,corresponding to 23 kinds of Western medicine diagnosis,the highest frequency was chronic superficial gastritis,followed by chronic atrophic gastritis.(2)Syndrome differentiation of deficiency and excess: mainly based on the syndrome of excess and deficiency.(3)TCM Syndrome Type: 328 times of TCM syndrome type diagnosis were recorded after standardization,and the highest frequency was spleen stomach damp heat syndrome,spleen stomach weakness syndrome,liver stagnation and qi stagnation syndrome.(4)Type of deficiency syndrome: mostly deficiency of Qi,followed by deficiency of Yin.4.Clinical manifestations of medical cases:(1)basic information: after standardized records,84 kinds of clinical manifestations were recorded,with a total frequency of 1418.Stomach pain,Nadia and belching were the most frequent accompanied symptoms.(2)Cluster analysis: it can be divided into 8 categories: 1: stomach stuffiness;2: stomachache,acid regurgitation and heartburn;3: stupor,loose stools and diarrhea,fatigue,nausea,emaciation,chills and sticky mouth;4: belching;5: dry mouth,bitter mouth,hypochondriac pain,irritability and irritability;6: insomnia,dizziness and heavy sleepiness;7: dry stools,chest tightness,noisy stomach,fullness under the flank and emotion Class 8: abdominal distention.(3)Association Rules: epistomach stuffiness,stomachache,Nadie,belching,loose stools and diarrhea,bitter mouth,dry mouth,insomnia,and dry stool are all chronic superficial gastritis and chronic atrophic gastritis,which are the high-frequency concomitant symptoms of epigastric disease.5.Rules of drug use:(1)basic information: 219 effective prescriptions for initial diagnosis are included in the study,involving 265 kinds of traditional Chinese medicine,and the frequency of published drugs is 3047 times,with an average of each prescription thirteen point nine one Among them,pinellia,Coptis and liquorice are the most frequently used.(2)Four properties analysis: the top three in the frequency of use are warm,mild and mild cold traditional Chinese medicine.(2)Five flavors analysis: the top three used frequency are bitter,pungent and sweet Chinese medicine.(3)Meridian analysis: the top three meridian frequency are spleen,stomach and lung.(4)Efficacy analysis: the top three frequency are dry dampness and resolve phlegm,heat clearing and detoxification,heat clearing and dampness drying.(5)Association rules of traditional Chinese medicine: Evodia rutaecarpa is the most frequent drug pair.(6)Cluster analysis: it can be divided into 14 categories: 1: pinellia,Coptis,Fructus aurantii,Scutellaria,cuttlebone,corydalis,tulip,Evodia,angelica,Ligusticum chuanxiong,Fructus Toosendan,Trichosanthes;2: Glycyrrhiza,White Peony Root,bupleurum;3: tangerine peel,Zhuru;4: Atractylodes macrocephala,Poria cocos,Amomum villosum;5: Magnolia,Atractylodes Rhizoma,Semen Raphani;6: Cyperus,Fructus aurantii,perilla stem;7: Malt,Shenqu,hawthorn;class 8: Jineijin,Radix Pseudostellariae,Ophiopogon japonicus;class 9: Finger Citron,Fruit Setariae Germinatus,Salvia miltiorrhiza;class10: dandelion,Hedyotis diffusa,coix seed,Huoxiang,Yinchen,Peilan;class11: dangshen,Zingiber;class 12: ginger;class 13: Arc Shell;class 14: Inula Flower,hematite.(7)Factor analysis: it can be divided into 10 categories:factor 1: Herba Artemisiae,Herba agastache,Peilan and Hedyotis diffusa;factor 2: Evodia rutaecarpa,cuttlebone and Coptis;factor 3: hematite and Inula Flower;factor 4: malt and Shenqu;factor 5: dangshen and Zingiber;factor 6: Angelica and Ligusticum chuanxiong;factor 7: Magnolia officinalis,pinellia and Fructus aurantii;factor 8: Radix Aucklandiae and Fructus Amomi;factor 9: Arc Shell;factor 10: perilla stem.(8)Association rules of clinical manifestations and drug use: Coptis chinensis is preferred for the treatment of anti acid,heartburn,bitter mouth,dry mouth and insomnia symptoms,Coptis chinensis and Pinellia ternata are preferred for the treatment of anti acid symptoms,Pinellia ternata is preferred for the treatment of nausea symptoms,licorice and Atractylodes macrocephala are commonly used for the treatment of fatigue symptoms.(9)Association rules of traditional Chinese medicine and Western medicine diagnosis: in the treatment and diagnosis of chronic superficial gastritis,Coptis chinensis,Pinellia ternata,tangerine peel,Fructus aurantii,white peony,Scutellaria,Magnolia officinalis,bupleurum,Cyperus,cuttlebone and Corydalis should be used well;in the treatment and diagnosis of chronic atrophic gastritis,Glycyrrhiza uralensis,Atractylodes macrocephala,Coptis,Cyperus,white peony,Hedyotis diffusa,Poria cocos Scutellaria baicalensis,malt,Magnolia officinalis and Amomum villosum are good for the treatment and diagnosis of stomach stuffiness corresponding to bile reflux gastritis.(10)Logistic regression analysis of syndrome type and traditional Chinese medicine: the drugs used for damp heat syndrome of spleen and stomach are Zhuru,Yinchen,Peilan,malt and yanhusuo in order;Chaihu and Pinellia in order for spleen and stomach weakness syndrome;Atractylodes macrocephala,Fructus aurantii and Radix Pseudostellariae in order for liver depression and qi stagnation syndrome.ConclusionStomach stuffiness is a common chronic disease of digestive system.In this study,data mining technology is used to analyze the etiology and pathogenesis of stomach stuffiness in modern times,and to explore the medication law contained in the treatment of stomach stuffiness.The basic pathogenesis of the present and contemporary stomach stuffiness is characterized by the deficiency of the original and the standard of the real.On the basis of the deficiency of the spleen and stomach qi,yin and Yang,it is mixed with various pathogenic factors such as dampness,heat,phlegm,blood stasis,stagnation,cold,food accumulation,etc.,so it presents the characteristics of protracted and refractory,easy to relapse.The pathogenesis of dampness and heat,spleen deficiency and liver depression are dominant.In the process of treatment,we should pay attention to the core pathogenesis,such as the combination of pain,cold and temperature,tonic and diarrhea,syndrome differentiation and treatment,and the elimination of PI.