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Analysis Of Endoscopic And Pathological Feature Of 268 Coloretalc Polyps In Different Age Groups

Posted on:2020-01-07Degree:MasterType:Thesis
Country:ChinaCandidate:Q LiuFull Text:PDF
GTID:2504306728998929Subject:Internal Medicine
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ObjectiveTo analyze the distribution of colorectal polyps at different ages in terms of growth site,size number and pathological types,and to explore the occurrence rules of colorectal polyps,so as to provide clinical basis for the early detection of colorectal cancer..MethodFrom September 2016 to December 2018,268 patients with colorectal polyps who underwent colonoscopy in the affiliated hospital of Tai Shan Medical College and had complete clinical data were selected.According to the age grouping criteria of the United Nations world health organization,268 patients with colorectal polyps were divided into the youth group(44 years old),the middle-aged group(45-59 years old)and the elderly group(60 years old).SPSS20.0 statistical software was used to the growth of colorectal polyps location,size,number and the pathological types and the relationship between age and data analysis,adoption or forming than said count data,and the comparison between the groups using chi-square Fisher’s exact probability method,P<0.05 difference was statistically significant,pairwise comparisons between groups using the Bonferroni method,inspection level is adjusted for P<0.0167,the difference was statistically significant.Results1.The polyp composition was 18.2%,35.1%and 46.7%in the youth group,the middle-aged group and the elderly group,respectively(χ~2=92.928,P<0.001).There were significant differences between the two groups:the youth group and the middle-aged group(χ~2=36.89,P<0.001),the youth group and the elderly group(χ~2=93.125,P<0.001),and the middle-aged group and the elderly group(χ~2=13.887,P<0.001).2.Analysis of polyp growth sites:a total of 501 polyps were detected in 268 patients,of which 177(35.3%)were located in the rectum,150(29.9%)in the sigmoid colon,70(14.0%)in the descending colon,54(10.8%)in the transverse colon,31(6.2%)in the ascending colon,and 19(3.8%)in the ileocecal region.There was no significant difference in colonic polyp growth site between different age groups(χ~2=9.897,P>0.05).3.Analysis of polyp diameter:there was no significant difference in the diameter of colorectal polyps in all age groups(χ~2=2.513,P=0.642).4.Analysis of polyp number(single or multiple):there were statistically significant differences in the number of polyps among different age groups(P<0.05).Pantwise comparison:there was no significant difference between the youth group and the middle-aged group(χ~2=0.102,P=0.750),the difference between the middle-aged group and the elderly group was statistically significant(χ~2=9.271,P=0.002),and the middle-aged group(χ~2=0.102,P=0.750),the difference between the middle-aged group and the elderly group was statistically significant(χ~2=9.271,P=0.002),and the difference between the elderly group and the youth group was statistically significant(χ~2=7.580,P=0.006).5.Analysis of pathological types of polyps:the pathological types of polyps in different age groups were statistically significant(χ~2=17.862,P=0.003).The incidence of adenomatous polyps in each age group was statistically significant(χ~2=16.297,P<0.001).There were significant differences between the youth group and the elderly group(χ~2=13.711,P<0.001)and the middle-aged group and the elderly group(χ~2=9.452,P=0.002).The incidence of proliferative polyps in each age group was statistically different(χ~2=9.064,P=0.011).There were statistically significant differences between the middle-aged group and the elderly group(χ~2=5.841,P=0.016),and between the young group and the elderly group(χ~2=7.847,P=0.005).There was no significant difference in the incidence of inflammatory polyps among age groups(χ~2=3.949,P=0.139).There was no statistically significant difference in the incidence of hamartoma polyps among age groups(χ~2=1.046,P=0.593).Conclusions1.Elderly patients are the main population of colorectal polyps,and the incidence of multiple polyps in elderly patients is higher than that in young and middle-aged patients.2.The incidence of hyperplastic polyps in young and middle-aged patients is higher than that in elderly patients.Adenomatous polyps are most common in elderly patients.3.There was no significant difference in the location and size of colorectal polyps in different age groups.
Keywords/Search Tags:Colorectal polyp, age, endoscopic examination, pathological classification
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