Self Made Desensitization Prescription In The Treatment Of Allergic Rhinitis Clinical Study Of Lung And Spleen Deficiency Syndrome

Objective:My tutor is an important inheritor of Li Kongding School of Traditional Chinese Medicine.As one of the inheritors of Sichuan School of Traditional Chinese Medicine,he has unique experience in the treatment of allergic rhinitis(deficiency of lung and spleen qi syndrome)and has summed up the empirical formula of "self-designed desensitization prescription".Through the observation of its safety and therapeutic effect in clinical studies,to provide the corresponding theoretical basis for the later use of this formula.Methods:56 patients from the outpatient department of respiratory department of Mianyang traditional Chinese medicine hospital(February 2019 to January 2021)were selected as the research objects,and they were divided into a treatment group and control group randomly,27 cases in the treatment group and 29 cases in the control group.The control group was given basic antihistamine treatment: ebastine tablets(Jiangsu Lianhuan Pharmaceutical Co.,Ltd.,national medicine Zhunzi h20040119)oral treatment,10 mg / time,once a day,before going to bed.On the basis of the control group,the treatment group was given self-made desensitization prescription.The total course of treatment was 14 days.Finally,statistical data,using spss25.0 software processing and analysis,compared two groups of TCM symptom score,VAS before and after treatment,at the same time compared two groups of TCM syndrome efficiency after treatment,observed the clinical efficacy and safety of "self desensitization formula".Results:1.Basic situation: the following two test methods were used for comparison:independent sample t test and chi square test.The results showed that there was no significant difference in age,course of disease and gender between the two groups,P > 0.05.2.VAS comparison: subjective VAS scores were performed in all patients.By Mann Whitney U test and Wilcoxon rank sum test,before treatment,there was no significant difference in VAS between the two groups.VAS and follow-up VAS of the treatment groups were markedly lower than those of the control group,after the treatment,VAS of the two groups were significantly lower than those before treatment.The difference was statistically significant(P < 0.05).3.Comparison of TCM symptoms and curative effect: by Mann Whitney U test and Wilcoxon rank sum test,before treatment,there was no evident difference in the syndrome score of the two groups—— both the syndrome score and follow-up syndrome score of the treatment group after treatment were significantly lower than those of the control group,and the syndrome score of the two groups after treatment were noticeably lower than those before treatment.4.Case shedding: the study removed a total of 60 cases of shedding cases,a total of56 cases were included,4 cases of shedding,accounting for 6.67% of the total included cases,in line with the scope of 10% of the experimental design requirements.Among them,3 cases fell off in the treatment group and 1 case fell off in the control group.All cases fell off within one week after treatment and were not included in the statistical range.5.Comparison of treatment effect: by Mann Whitney U test and chi square test,the curative effect of the treatment group was better than that of the control group,the effective rate after treatment and follow-up effective rate were significantly higher than that of the control group,and there was no evident difference in recurrence rate between the two groups.6.There were no obvious adverse events and side effects in the two groups.Conclusion:The clinical symptoms of patients with allergic rhinitis(lung and spleen qi deficiency syndrome)were effectively improved after the self-designed desensitization prescription treatment,which proved that the treatment of allergic rhinitis with western medicine alone was significantly less effective in alleviating patients’ subjective symptoms and improving the efficiency of TCM syndromes than the combined treatment of western medicine.Therefore,the self-designed desensitization prescription has its unique advantages in the treatment of allergic rhinitis and is worthy of being widely used.