Clinical Observation Of Shenqi Fuzheng Injection In The Treatment Of Qi Deficiency Syndrome In Elderly Diseases

ObjectiveTo provide a basis for the clinical promotion of Shenqi Fuzheng Injection in the treatment of senile diseases MethodsThrough a randomized,double-blind,single center controlled study,50 inpatients in the First Affiliated Hospital of Guangzhou University of traditional Chinese medicine from May 1,2019 to June 30,2021 who met the diagnostic criteria of senile Qi deficiency syndrome and the inclusion criteria were randomly divided into two groups.The control group was treated with compound amino acid injection and the experimental group was treated with Shenqi Fuzheng injection,Taking TCM Qi deficiency syndrome score,six minute walking distance,fatigue scale score and activity of daily living score as evaluation indexes,this paper discusses the effectiveness of Shenqi Fuzheng Injection for elderly Qi deficiency syndrome,and records the adverse reactions in the test process.Results1.Comparison of basic conditions before treatment: there was no significant difference between the two groups in gender,age,body mass index,hemoglobin,serum albumin,Qi deficiency syndrome score,fatigue scale score and disease catogory before treatment(P > 0.05).2.Clinical efficacy: Curative effect of qi deficiency syndrome of traditional Chinese medicine: the short-term curative effect,the effective rates of the experimental group and the control group were 78.3% and 79.2% respectively,and the difference was not statistically significant(P > 0.05).The effective rates of the two groups were 69.6% and25% respectively.The experimental group was significantly better than the control group(P< 0.05).3.Comparison of TCM symptom score of qi deficiency syndrome: the symptom score of TCM syndrome in the two groups decreased after treatment,the difference within the group was statistically significant(P < 0.05),and there was no significant difference between the two groups after treatment(P > 0.05).The comparison of five symptoms of shortness of breath,mental fatigue,fatigue,spontaneous sweating and lazy speech between the two groups before and after treatment showed that a certain proportion of single symptoms of qi deficiency disappeared.The disappearance rate of fatigue index in the experimental group was slightly higher than that in the control group;During the follow-up,the total score of qi deficiency symptoms and the three symptoms of shortness of breath,mental fatigue and fatigue in the experimental group were better than those in the control group(P < 0.05),the difference was statistically significant,and there was no significant difference in the two symptoms of fatigue and lazy speech(P > 0.05).4.Comparison of six minute walking distance: after treatment,the six minute walking distance of the two groups increased compared with that before treatment(P < 0.05);There was no significant difference between the two groups after treatment(P > 0.05).5.Comparison of fatigue scale score: the total score of fatigue scale in the two groups decreased significantly after treatment.There was significant difference between the two groups(P < 0.05),but there was no significant difference between the two groups(P >0.05).The scores of body fatigue in the two groups decreased after treatment(P < 0.05),the difference was statistically significant,and there was no significant difference between the two groups(P > 0.05).Compared with mental fatigue,the scores of the two groups decreased after treatment.There was significant difference before and after treatment in the experimental group(P < 0.05).There was no significant difference before and after treatment in the control group(P > 0.05);There was no significant difference between the two groups(P > 0.05).6.Activity of daily living scale: there was no significant difference between the two groups before and after treatment(P > 0.05).7.Related immune indexes: the immune indexes Ig A,Ig M and SOD of the two groups were compared within and between the two groups,and the difference was not statistically significant(P > 0.05).Among them,the indexes of Ig A and SOD increased after treatment.8.Safety index comparison: no obvious adverse reactions occurred in the two groups during the treatment,and the patients in the two groups were in the safe range.ConclusionShenqi Fuzheng injection has obvious advantages in the treatment of qi deficiency syndrome of elderly diseases in the medium and long term.It shows obvious treatment effect in the three indicators of shortness of breath,mental fatigue and fatigue.It can improve the symptoms of patients’ body fatigue,especially in terms of mental fatigue.It can improve the six minute walking distance and improve the symptom score of qi deficiency syndrome in traditional Chinese medicine,The treatment of qi deficiency syndrome in elderly diseases is effective and safe,which is worthy of in-depth research and popularization.