Clinical Study Of Qicangkubo Decoction Retention Enema In The Treatment Of Ulcerative Colitis (Spleen Deficiency And Dampness Obstruction Syndrome)

Objective:This topic applies the Qicangkubo Decoction retention enema to treat ulcerative colitis(spleen deficiency and dampness obstruction syndrome).The effectiveness and security of Qicangkubo Decoction in the therapy of this disease,and the theoretical basis and mode of action of this prescription in the therapy of ulcerative colitis were preliminarily investigated,which supplied dialectical basis and clinical evidence for the therapy of ulcerative colitis with TCM retention enema.Methods: Totally 60 patients from the Department of Gastrointestinal Endoscopy,Shandong Provincial Hospital of TCM who met the case selection criteria were selected and divided into an treatment group and a control group according to random drawing,with 30 cases in each group.The control group was supplied basic therapy(oral mesalazine enteric-coated tablets,1.5g/day),and the treatment group was supplied Qicangkubo Decoction retention enema with the therapy of the control group,14 days as a course of treatment.Both groups received 4 courses of treatment.After the therapy,the data of the two groups of patients were collected,and the TCM symptom score,Baron score,Mayo score,ESR,CRP and other data before and after the experiment were compared in the two groups of patients,and IBM SPSS 26.0 software was selected to process the above data.Results: The observation indexes of the treatment group and the control group were considerably enhanced compared with those before therapy(P<0.01).After inter group control,the treatment group was considerably better than the control group in the total score of traditional Chinese medicine symptoms(P< 0.01),and better than the control group in the improvement of TCM syndrome curative effect,comprehensive curative effect,modified Mayo score,Baron score,C-reactive protein and ESR(P < 0.05).Conclusion:The clinical efficacy of retention enema of Qicangkubo Decoction combined with mesalazine enteric-coated tablets in the treatment of ulcerative colitis(spleen deficiency and dampness resistance syndrome)is better than that of mesalazine enteric-coated tablets alone.It can be used as a new method for the treatment of ulcerative colitis,and is worthy of clinical application.