Professor CAI Lin’s Academic Thoughts On Treating Chronic Gastritis Are Based On The Ascending And Descending Of Qi Movement And Summary Of Medication Regularity

Objective:By collecting the cases of chronic gastritis treated by Professor Cai Lin based on the ascending and descending of qi movement in the outpatient department,with the help of data mining system,the medication regularity was analyzed,and the medication experience of Professor Cai Lin based on the ascending and descending of qi movement in the treatment of chronic gastritis was further summarized in order to provide clinicians with new ideas.Method:1.Through systematic study of ancient books such as Huang Di Nei Jing,Spleen and Stomach Theory,Treatise on Febrile Diseases,and Shi Sheng Xin Yuan,the understanding of ancient and modern physicians on the theory of the ascending and descending of qi movement was sorted out,and at the same time,in combination with the etiology and pathogenic characteristics of chronic gastritis,according to the pivot of the ascending and descending of qi movement,the academic thoughts of Professor Cai Lin on the treatment of chronic gastritis from the ascending and descending of qi movement were systematically summarized.2.Through the screening and analysis of Professor Cai Lin prescriptions for the treatment of chronic gastritis,231 outpatient prescriptions for the treatment of chronic gastritis from the ascending and descending of qi movement were selected,the prescription information was entered into an Excel table,a database was established,and the regularity of prescription medication was data mined using the Traditional Chinese Medicine Inheritance Support Platform(V3.0)system.Result:Professor Cai Lin ’s commonly used drugs,commonly used prescriptions and correlations between drugs for the treatment of chronic gastritis from the ascending and descending of qi movement are as follows:1.General conditions:A total of 231 eligible patients with chronic gastritis were included this research,including 79 males and 152 females,with a male to female ratio of 1:1.92.The age distribution of the study subjects was between 18 and 86 years,with the majority of them are aged 40 to 59 years.2.Frequency analysis:A total of 231 prescriptions were included in this research,involving 106 kinds of traditional Chinese medicines,with a total frequency of 3907 times,of which the top ten Chinese medicinesused more frequently were:Poria cocos,Glycyrrhiza uralensis,Atractylodes macrocephala,Perilla frutescens,Bupleurum chinense,Codonopsis pilosula,Jujube,Pinellia ternata,Citrus sinensis,and Astragalus membranaceus.The vast majority of these drugs enter the spleen meridian to help the spleen lift,Bupleurum chinense enters the liver meridian to regulate qi,and Astragalus membranaceus and Perilla frutescens enter the lung meridian to disperse the upper energizer qi.The top four prescriptions with higher frequency of use were Huoxiang Zhengqi San,Chaiping San,Xiangsha Liujunzi Decoction,and Chaihu Guizhi Decoction.For the traditional Chinese medicines involved,the frequency of taste meridians and efficacy use was ranked from high to low,the four qi were warm,flat,cold,hot,and cool;the five flavors were pungent,sweet,bitter,and salty;It reflects the treatment concept of invigorating qi and promoting qi.the meridians were spleen meridian,lung meridian,stomach meridian,liver meridian,heart meridian,kidney meridian,large intestine meridian,gall bladder meridian,small intestine meridian,and triple energizer meridian,without pericardial meridian medication;It objectively reflects Professor Cai Lin’s idea of treating chronic gastritis based on spleen ascending and stomach descending,liver ascending and lung descending.and the efficacy was tonic drugs,antidotes,qi drugs,phlegm drugs,digestion drugs,dampness drugs,water and dampness drugs,Wenli drugs,heat-clearing drugs,hemostatic drugs,and expelling wind and damp drugs.3.Association analysis:Through drug association analysis,it was found that Professor Cai Lin’s most commonly used 2,3,4 flavors,and drug combinations were:Invigorating spleen and invigorating qi:Poria cocos→Atractylodes macrocephala(170 times);Invigoratingspleen and promoting qi:Poria cocos→Atractylodes macrocephala Koidz,Perilla frutescens(136 times);Poria cocos→Atractylodes macrocephala,Perilla frutescens,and Bupleurum chinense(103 times).4.Cluster analysis:based on an unsupervised entropy hierarchical clustering algorithm,four new prescriptions for the treatment of chronic gastritis from the ascending and descending of qi movement were obtained,which were:①:Poria cocos,Atractylodes macrocephala,Codonopsis pilosula,Perilla frutescens,Astragalus membranaceus,and Pinellia ternate,which were suitable for Chronic gastritis of spleen-stomach qi deficiency type;②:Bupleurum chinense,Atractylodes macrocephala,Poria cocos,Perilla frutescens,Hawthorn,and Glycyrrhiza uralensis,which were suitable for chronic gastritis of liver-stomach qi stagnation type.③Radix Bupleuri,Radix PaeoniaeAlba,Radix Glycyrrhizae,Fructus Evodiae,Rhizoma Atractylodis Macrocephalae,and Jujube are suitable for chronic gastritis of liver-qi offending stomach with vomiting and swallowing type;④:Huoxiang,Rhizoma Pinelliae,Citrus sinensis,Jujube,Perilla frutescens leaves,and Zingiber officinale are suitablefor chronic gastritis of spleen-stomach deficiency cold type.Conclusion:1.In this Research,the general results showed that female patients with chronic gastritis would be significantly more than male patients;the age of onset was mostly concentrated between 40 and 59 years.2.Analyze the four qi,five flavors and meridians of all the traditional Chinese medicines included in this Research,and conclude that Professor Cailin’s treatment of chronic gastritis from the ascending and descending of qi movement is mainly based on warm and peaceful drugs,with pungent and sweet taste being the most used;the large logarithm belongs to the spleen and stomach,lung and liver meridians;3.Professor Cai Lintreatment of chronic gastritis from the ascending and descending of qi movement has three main treatment experiences:the ascending and descending of qi movement,in order to balance a period of time;pay attention to soothing the liver;do not forget to promote the lung;Therefore,the method of regulating qi should not only take care of the nature of the ascending and descending of movement viscera’s qi,but also pay attention to "phlegm","blood stasis","dampness" and other real pathogens to block qi.