Clinical Evaluation Of Modified Painless Wheat Granule Purulent Moxibustion Combined With Traditional Chinese Medicine In The Treatment Of Chronic Non-atrophicGastritis Of Spleen And Stomach Deficiency Cold Type

Objective:To observe and compare the cl ini cal efficacy of improved painless wheat grain suppurative moxibustion combined with Huangqi Jianzhong Decoction and simple Huangqi Jianzhong Decoction in the treatment of chronic non-atrophic gastritis(CNAG)of spleen and stomach deficiency and cold type,so as to evaluate the improved painless wheat grain suppurative moxibustion The clinical curative effect and safety,and a preliminary analysis of its mechanism of action,to provide a clinical treatment of CNAG with both application and popularization of TCM and external therapy.Methods:A total of 72 patients with spleen and stomach deficiency cold type CNAG were included in this study,and were randomly divided into improved painless wheat purulent moxibustion group(treatment group)and traditional Chinese medicine group(control group)according to random number table method,with 36 cases in each group.The control group was treated with Huangqi Jianzhong decoction;The treatment group was combined with improved painless wheat kernel suppurating moxibustion on the basis of Huangqi Jianzhong Decoction treatment,and selected Zhongwan,Zusanli and Pishu points.The treatment course of both groups was 1 month.The scores of TCM symptoms and signs,physical scores(PCS)and psychological scores(MCS)in the SF-36 scale were recorded and compared between the two groups before treatment,after treatment and at follow-up(1 month after treatment),respectively.The clinical efficacy of the two groups was evaluated and compared 1 month after treatment.Statistical software SPSS25.0 was used for data analysis.Results:1.TCM symptom and sign scores:The simple effect of TCM symptom and sign scores before treatment was not significant in the two groups(P>0.05),which was comparable.The simple effect was significant after treatment and 1 month after treatment(P<0.05).The simple effect of observation points in the treatment group and the control group was significant(P<0.001),the scores of the two groups were significant with the group and the observation time point,and the interaction effect between the observation time point and the group was significant,indicating that the scores of TCM symptoms and signs of the two groups after treatment and one month after treatment were statistically significant,and were comparable between the two groups.In addition,it can be more intuitively observed from the line chart that the scores of TCM symptoms and signs of the two groups continue to decrease after treatment and at the follow-up of 1 month after treatment,and the reduction rate is faster during the treatment period and slower after the treatment course,and in the treatment period and 1 month after the treatment course,the scores of the treatment group are more significantly reduced than the control group.These results indicated that both groups of treat ment could improve the clinical symptoms of patients in a long term and continuously,but the therapeutic effect of modified painless moxibustion with wheat kernel pus was superior to that of traditional Chinese medicine alone.2.PCS and MCS scores:the simple effects of PCS and MCS scores of the two groups before treatment were not significant,which were comparable.After treatment and one month after the end of the course of treatment,the intergroup effect,time effect and interaction effect of PCS and MCS scores of the two groups were statistically significant,indicating that with the progress of the course of treatment,the physiological and psychological state of the two groups were improved,and there was comparability between the two groups.From the line chart,we can also see that the PCS and MCS scores of the treatment group are more obvious than those of the control group,indicating that the combination of modified painless wheat granulation purulent moxibustion therapy can better improve the mental and physical health status of patients.3.Clinical efficacy evaluation:after the course of treatment,the total effective rate of the treatment group was 90.91%,and that of the control group was 75.76%;the total effective rate of the treatment group was 96.97%,and that of the control group was 81.82%;The curative effect was better than that of the control group(P<0.05).4.Safety evaluation:During the test period,the vital signs of the two groups showed no obvious abnormalities.There were no adverse react ions or accidents related to the modified painless grain suppuration moxibustion treatment.It shows that the improved painless grain suppuration moxibustion is safe.Conclusion:The two groups of treatment can effectively improve the clinical symptoms and quality of life of CNAG of spleen and stomach deficiency cold type,and both have certain long-term effects,and the clinical effects are definite.Modified painless wheat granule purulent moxibustion combined with Huangqi Jianzhong decoction is superior to simple traditional Chinese medicine in improving patients’symptoms,improving quality of life and long-term clinical effect,and the safety is good.The improved painless wheat granulation purulent moxibustion is worth popularizing in clinic.